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Vol 80, No 4 (2009)
ARTICLES
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The course of pregnancy, delivery and puerperium in a woman with multifactorial thrombophilia – a case report

Magdalena Barlik, Krzysztof Drews, Agnieszka Seremak-Mrozikiewicz
Ginekol Pol 2009;80(4).

open access

Vol 80, No 4 (2009)
ARTICLES

Abstract

Summary Hereditary or acquired thrombophilia may induce many complications in pregnant women, the relationship between thrombophilia and recurrent miscarriages as well as intrauterine death in the second half of the pregnancy being identified as a particularly frequent one. The introduction of detailed diagnostic methods in women with pregnancy loss in anamnesis allow for more frequent recognition of multifactorial thrombophilia. However, uniform recommendations connected with pregnancy course in these cases, application of anticoagulation prophylaxis and optimal dosage are lacking. In this manuscript we have described the course of a pregnancy, delivery and puerperium of a pregnant woman with recurrent miscarriages in anamnesis, antiphospholipid syndrome, being simultaneously a carrier of both - Leiden (1691G>A) and 20210G>A prothrombin mutations - (multifactorial thrombophilia), in which anticoagulant prophylaxis has been successfully applied.

Abstract

Summary Hereditary or acquired thrombophilia may induce many complications in pregnant women, the relationship between thrombophilia and recurrent miscarriages as well as intrauterine death in the second half of the pregnancy being identified as a particularly frequent one. The introduction of detailed diagnostic methods in women with pregnancy loss in anamnesis allow for more frequent recognition of multifactorial thrombophilia. However, uniform recommendations connected with pregnancy course in these cases, application of anticoagulation prophylaxis and optimal dosage are lacking. In this manuscript we have described the course of a pregnancy, delivery and puerperium of a pregnant woman with recurrent miscarriages in anamnesis, antiphospholipid syndrome, being simultaneously a carrier of both - Leiden (1691G>A) and 20210G>A prothrombin mutations - (multifactorial thrombophilia), in which anticoagulant prophylaxis has been successfully applied.
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Keywords

pregnancy, multifactorial thrombophilia, antithrombotic prophylaxis

About this article
Title

The course of pregnancy, delivery and puerperium in a woman with multifactorial thrombophilia – a case report

Journal

Ginekologia Polska

Issue

Vol 80, No 4 (2009)

Bibliographic record

Ginekol Pol 2009;80(4).

Keywords

pregnancy
multifactorial thrombophilia
antithrombotic prophylaxis

Authors

Magdalena Barlik
Krzysztof Drews
Agnieszka Seremak-Mrozikiewicz

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