Vol 80, No 5 (2009)
ARTICLES
Inflammatory bowel diseases in pregnancy
Marek Hartleb, Krzysztof Gutkowski
Vol 80, No 5 (2009)
ARTICLES
Abstract
Summary Ulcerative colitis (CU) and Crohn’s disease (CD) are called inflammatory bowel diseases (IBD). In the light of contemporary knowledge it is believed that a common feature of CU and CD is chronic gut inflammation which is the result of a combination of genetic, immunologic and environmental factors. CU and CD incidence peak is observed in the age group from 20 to 40 and, therefore, women in reproductive age consititute the bulk of it. Dagnostics is based on biochemical, endoscopic and histologic examinations whereas treatment is based on longterm anti-inflammatory and immunosuppressive pharmacotherapy. Knowledge of the influence of IBD on pregnancy course and proper treatment allows us to reduce the risk of serious obstetric complications and significant adverse reactions to medication. In this review we discuss the issue of inflammatory bowel diseases affecting pregnant women, their impact on pregnancy and risk of obstetrical complications, as well as pharmacotherapy safety issues.
Abstract
Summary Ulcerative colitis (CU) and Crohn’s disease (CD) are called inflammatory bowel diseases (IBD). In the light of contemporary knowledge it is believed that a common feature of CU and CD is chronic gut inflammation which is the result of a combination of genetic, immunologic and environmental factors. CU and CD incidence peak is observed in the age group from 20 to 40 and, therefore, women in reproductive age consititute the bulk of it. Dagnostics is based on biochemical, endoscopic and histologic examinations whereas treatment is based on longterm anti-inflammatory and immunosuppressive pharmacotherapy. Knowledge of the influence of IBD on pregnancy course and proper treatment allows us to reduce the risk of serious obstetric complications and significant adverse reactions to medication. In this review we discuss the issue of inflammatory bowel diseases affecting pregnant women, their impact on pregnancy and risk of obstetrical complications, as well as pharmacotherapy safety issues.
Keywords
Inflammatory bowel diseases, ulcreative colitis, Crohn disease
Title
Inflammatory bowel diseases in pregnancy
Journal
Ginekologia Polska
Issue
Vol 80, No 5 (2009)
Page views
529
Article views/downloads
566
Bibliographic record
Ginekol Pol 2009;80(5).
Keywords
Inflammatory bowel diseases
ulcreative colitis
Crohn disease
Authors
Marek Hartleb
Krzysztof Gutkowski
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