open access

Vol 80, No 8 (2009)
ARTICLES
Get Citation

Analysis of risk factors for nosocomial infections in the Neonatal Intensive Care Unit of the Pomeranian Medical University in Szczecin in the years 2005-2008

Halina Konefał, Diana Sochaczewska, Beata M. Czeszyńska, Tomasz Elster, Elżbieta Baryła-Oankiewicz
Ginekol Pol 2009;80(8).

open access

Vol 80, No 8 (2009)
ARTICLES

Abstract

Summary The aim of the study was to assess the significance of some perinatal risk factors and neonatal complications in occurrence of nosocomial infections in the population of NICU patients. Material and methods: Analysis of risk factors was performed in all patients treated in the years 2005-2008 in NICU Department of the Pomeranian Medical University in Szczecin, Poland. Five hundred and seventeen neonates divided into groups with and without occurrence of nosocomial infection were included into the study. Results: Seventy nine (15.28%) neonates developed nosocomial infection. Among them pneumonia (56.96%) and sepsis (21.5%) were the most common. The proportion of Gram-positive and Gram negative organisms were 44.3% and 50.6% respectively. The main risk factor for nosocomial infection was colonization (sensitivity - 100% and specificity – 94.75%). Univariate analysis showed that premature rupture of fetal membrane, GA< 32 hbd, birthweight <2000g, respiratory insufficiency, intracranial hemorrhages and oral feeding intolerance were associated with the development of nosocomial infection. Multivariate stepwise logistic regression analysis showed that mechanical ventilation – OR 9,42 [4,45-19,96] p<0,0001, intracranial hemorrhages – OR 4,12 [2,21-7,67] p<0,0001, necessity of Infant-Flow method - OR 3,32 [1,82-6,06] p<0,0001or n-CPAP method - OR 1,92 [1,07-3,44] p<0,05, necrotizing enterocolitis – OR 2,38 [1,17-4,87] p<0,05 and intrauterine hypotrophy - OR 1,8 [1,07-3,76] p<0,05 were sets of predicted factors for the development of nosocomial infection. We conclude that colonization of NICU patients with hospital pathogens is the most important risk factor of nosocomial infection incidence. Besides colonization, significant additional risk factors for nosocomial infection were mechanical ventilation, intraventricular hemorrhages, low birth weight and low gestational age.

Abstract

Summary The aim of the study was to assess the significance of some perinatal risk factors and neonatal complications in occurrence of nosocomial infections in the population of NICU patients. Material and methods: Analysis of risk factors was performed in all patients treated in the years 2005-2008 in NICU Department of the Pomeranian Medical University in Szczecin, Poland. Five hundred and seventeen neonates divided into groups with and without occurrence of nosocomial infection were included into the study. Results: Seventy nine (15.28%) neonates developed nosocomial infection. Among them pneumonia (56.96%) and sepsis (21.5%) were the most common. The proportion of Gram-positive and Gram negative organisms were 44.3% and 50.6% respectively. The main risk factor for nosocomial infection was colonization (sensitivity - 100% and specificity – 94.75%). Univariate analysis showed that premature rupture of fetal membrane, GA< 32 hbd, birthweight <2000g, respiratory insufficiency, intracranial hemorrhages and oral feeding intolerance were associated with the development of nosocomial infection. Multivariate stepwise logistic regression analysis showed that mechanical ventilation – OR 9,42 [4,45-19,96] p<0,0001, intracranial hemorrhages – OR 4,12 [2,21-7,67] p<0,0001, necessity of Infant-Flow method - OR 3,32 [1,82-6,06] p<0,0001or n-CPAP method - OR 1,92 [1,07-3,44] p<0,05, necrotizing enterocolitis – OR 2,38 [1,17-4,87] p<0,05 and intrauterine hypotrophy - OR 1,8 [1,07-3,76] p<0,05 were sets of predicted factors for the development of nosocomial infection. We conclude that colonization of NICU patients with hospital pathogens is the most important risk factor of nosocomial infection incidence. Besides colonization, significant additional risk factors for nosocomial infection were mechanical ventilation, intraventricular hemorrhages, low birth weight and low gestational age.
Get Citation

Keywords

neonatal intensive care unit, nosocomial infection, risk factor

About this article
Title

Analysis of risk factors for nosocomial infections in the Neonatal Intensive Care Unit of the Pomeranian Medical University in Szczecin in the years 2005-2008

Journal

Ginekologia Polska

Issue

Vol 80, No 8 (2009)

Bibliographic record

Ginekol Pol 2009;80(8).

Keywords

neonatal intensive care unit
nosocomial infection
risk factor

Authors

Halina Konefał
Diana Sochaczewska
Beata M. Czeszyńska
Tomasz Elster
Elżbieta Baryła-Oankiewicz

Regulations

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk
tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl