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Vol 80, No 9 (2009)
ARTICLES
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Rapid assessment of the IL-6 cervico-vaginal fluid level in threatening preterm labor

Aneta Cymbaluk, Małgorzata Bartoszek, Sebastian Kwiatkowski, Ryszard Czajka, Andrzej Torbe, Rafał Rzepka
Ginekol Pol 2009;80(9).

open access

Vol 80, No 9 (2009)
ARTICLES

Abstract

Summary Objectives: The aim of the study was to check the cervico-vaginal fluid IL-6 levels using rapid, quantitive test in patients with threatening preterm labor, before and after tocolytic treatment. Material and methods: Sixty seven singular pregnant women, between 24 and 36 weeks of gestation, were included into the clinical trial. 35 women who were admitted to the Department due to clinical symptoms of threatened preterm labor formed the study group. 32 women between 24 and 36 gestational week, with uncomplicated pregnancy, formed the control group. Levels of IL-6 were measured just after material collection, using fast, quantitative spectrofotometric test. Results: The cervico-vaginal IL-6 level was higher in the study group (458pg/mL vs 123pg/mL; p<0.05). A significant reduction of cervico-vaginal IL-6 level was observed after two days of tocolytic treatment. Conclusion: A bedside, quantitative spectrofotometric method allows for a quick and repeatable assessment of cervico-vaginal IL-6 levels to establish the risk of preterm labor, as well as enables the monitoring of the effectiveness of tocolytic treatment.

Abstract

Summary Objectives: The aim of the study was to check the cervico-vaginal fluid IL-6 levels using rapid, quantitive test in patients with threatening preterm labor, before and after tocolytic treatment. Material and methods: Sixty seven singular pregnant women, between 24 and 36 weeks of gestation, were included into the clinical trial. 35 women who were admitted to the Department due to clinical symptoms of threatened preterm labor formed the study group. 32 women between 24 and 36 gestational week, with uncomplicated pregnancy, formed the control group. Levels of IL-6 were measured just after material collection, using fast, quantitative spectrofotometric test. Results: The cervico-vaginal IL-6 level was higher in the study group (458pg/mL vs 123pg/mL; p<0.05). A significant reduction of cervico-vaginal IL-6 level was observed after two days of tocolytic treatment. Conclusion: A bedside, quantitative spectrofotometric method allows for a quick and repeatable assessment of cervico-vaginal IL-6 levels to establish the risk of preterm labor, as well as enables the monitoring of the effectiveness of tocolytic treatment.
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Keywords

premature labor, interleukin 6, cytokines

About this article
Title

Rapid assessment of the IL-6 cervico-vaginal fluid level in threatening preterm labor

Journal

Ginekologia Polska

Issue

Vol 80, No 9 (2009)

Bibliographic record

Ginekol Pol 2009;80(9).

Keywords

premature labor
interleukin 6
cytokines

Authors

Aneta Cymbaluk
Małgorzata Bartoszek
Sebastian Kwiatkowski
Ryszard Czajka
Andrzej Torbe
Rafał Rzepka

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