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Vol 80, No 10 (2009)
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Noninvasive prenatal diagnosis from maternal plasma in serological conflicts in Poland: current practice and future prospects

Ewa Brojer, Katarzyna Guz, Agnieszka Orzińska
Ginekol Pol 2009;80(10).

open access

Vol 80, No 10 (2009)
ARTICLES

Abstract

Abstract The principles and results of noninvasive prenatal diagnosis in serological conflicts in Poland were described in the following work. Noninvasive fetal genotyping from plasma of immunized mother identifies women carrying fetus without incompatible antigen and risk of hemolytic disease. The presence of fetal RHD gene or RHCE*c/E alleles in maternal plasma is examined routinely in Institute of Hematology and Blood Transfusion in Warsaw. Preliminary results of successful fetal KEL*1 genotyping from maternal blood were obtained.

Abstract

Abstract The principles and results of noninvasive prenatal diagnosis in serological conflicts in Poland were described in the following work. Noninvasive fetal genotyping from plasma of immunized mother identifies women carrying fetus without incompatible antigen and risk of hemolytic disease. The presence of fetal RHD gene or RHCE*c/E alleles in maternal plasma is examined routinely in Institute of Hematology and Blood Transfusion in Warsaw. Preliminary results of successful fetal KEL*1 genotyping from maternal blood were obtained.

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Keywords

prenatal diagnosis, hemolytic disease of newborn, Genetic Techniques, Rh-Hr Blood-Group System

About this article
Title

Noninvasive prenatal diagnosis from maternal plasma in serological conflicts in Poland: current practice and future prospects

Journal

Ginekologia Polska

Issue

Vol 80, No 10 (2009)

Page views

620

Article views/downloads

1682

Bibliographic record

Ginekol Pol 2009;80(10).

Keywords

prenatal diagnosis
hemolytic disease of newborn
Genetic Techniques
Rh-Hr Blood-Group System

Authors

Ewa Brojer
Katarzyna Guz
Agnieszka Orzińska

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