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Vol 81, No 1 (2010)
ARTICLES
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Peritoneal fluid iron levels in women with endometriosis

Grzegorz Polak, Iwona Wertel, Rafał Tarkowski
Ginekol Pol 2010;81(1).

open access

Vol 81, No 1 (2010)
ARTICLES

Abstract

Summary Aim: Endometriosis is characterized by a cyclic hemorrhage within the peritoneal cavity. Accumulating data suggests that iron homeostasis in the peritoneal cavity may be disrupted by endometriosis. The aim of our study was to evaluate iron levels in peritoneal fluid (PF) of women with and without endometriosis. Material and Methods: Seventy-five women were studied: 50 women with endometriosis and, as a reference group, 25 patients with functional follicle ovarian cysts. Iron concentrations in the PF were measured using a commercially available colorimetric assay kit. Results: Iron concentrations were significantly higher in PF from women with endometriosis as compared to the reference group. Patients with stages III/IV endometriosis had significantly higher PF iron concentrations than women with stages I/II of the disease. Conclusions: Disrupted iron homeostasis in the peritoneal cavity of women with endometriosis plays a role in the pathogenesis of the disease.

Abstract

Summary Aim: Endometriosis is characterized by a cyclic hemorrhage within the peritoneal cavity. Accumulating data suggests that iron homeostasis in the peritoneal cavity may be disrupted by endometriosis. The aim of our study was to evaluate iron levels in peritoneal fluid (PF) of women with and without endometriosis. Material and Methods: Seventy-five women were studied: 50 women with endometriosis and, as a reference group, 25 patients with functional follicle ovarian cysts. Iron concentrations in the PF were measured using a commercially available colorimetric assay kit. Results: Iron concentrations were significantly higher in PF from women with endometriosis as compared to the reference group. Patients with stages III/IV endometriosis had significantly higher PF iron concentrations than women with stages I/II of the disease. Conclusions: Disrupted iron homeostasis in the peritoneal cavity of women with endometriosis plays a role in the pathogenesis of the disease.
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Keywords

endometriosis, iron, peritoneal fluid

About this article
Title

Peritoneal fluid iron levels in women with endometriosis

Journal

Ginekologia Polska

Issue

Vol 81, No 1 (2010)

Bibliographic record

Ginekol Pol 2010;81(1).

Keywords

endometriosis
iron
peritoneal fluid

Authors

Grzegorz Polak
Iwona Wertel
Rafał Tarkowski

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