Vol 81, No 1 (2010)
ARTICLES
Peritoneal fluid iron levels in women with endometriosis
Grzegorz Polak, Iwona Wertel, Rafał Tarkowski
Vol 81, No 1 (2010)
ARTICLES
Abstract
Summary Aim: Endometriosis is characterized by a cyclic hemorrhage within the peritoneal cavity. Accumulating data suggests that iron homeostasis in the peritoneal cavity may be disrupted by endometriosis. The aim of our study was to evaluate iron levels in peritoneal fluid (PF) of women with and without endometriosis. Material and Methods: Seventy-five women were studied: 50 women with endometriosis and, as a reference group, 25 patients with functional follicle ovarian cysts. Iron concentrations in the PF were measured using a commercially available colorimetric assay kit. Results: Iron concentrations were significantly higher in PF from women with endometriosis as compared to the reference group. Patients with stages III/IV endometriosis had significantly higher PF iron concentrations than women with stages I/II of the disease. Conclusions: Disrupted iron homeostasis in the peritoneal cavity of women with endometriosis plays a role in the pathogenesis of the disease.
Abstract
Summary Aim: Endometriosis is characterized by a cyclic hemorrhage within the peritoneal cavity. Accumulating data suggests that iron homeostasis in the peritoneal cavity may be disrupted by endometriosis. The aim of our study was to evaluate iron levels in peritoneal fluid (PF) of women with and without endometriosis. Material and Methods: Seventy-five women were studied: 50 women with endometriosis and, as a reference group, 25 patients with functional follicle ovarian cysts. Iron concentrations in the PF were measured using a commercially available colorimetric assay kit. Results: Iron concentrations were significantly higher in PF from women with endometriosis as compared to the reference group. Patients with stages III/IV endometriosis had significantly higher PF iron concentrations than women with stages I/II of the disease. Conclusions: Disrupted iron homeostasis in the peritoneal cavity of women with endometriosis plays a role in the pathogenesis of the disease.
Keywords
endometriosis, iron, peritoneal fluid
Title
Peritoneal fluid iron levels in women with endometriosis
Journal
Ginekologia Polska
Issue
Vol 81, No 1 (2010)
Page views
620
Article views/downloads
3420
Bibliographic record
Ginekol Pol 2010;81(1).
Keywords
endometriosis
iron
peritoneal fluid
Authors
Grzegorz Polak
Iwona Wertel
Rafał Tarkowski
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