Vol 81, No 5 (2010)
ARTICLES

open access

Page views 623
Article views/downloads 4245
Get Citation

Connect on Social Media

Connect on Social Media

Influence of vaginal biocoenosis on the presence of persistent atypical squamous cells and atypical glandular cells in Pap smear – a 3-year study

Inga Ludwin, Artur Ludwin, Antoni Basta
Ginekol Pol 2010;81(5).

Abstract

Abstract Aim of the study: the evaluation of influence of abnormal vaginal biocoenosis on presence and maintenance ASC and AGC in Pap smears. Methods: The study group consisted of 242 non-pregnant women (25-65 years of age): 207 women (4.96%) with atypical sqamous cells and 35 (0.7%) with atypical glandular cells. In all women the vaginal flora was assessed by Nugent scale. Results: Vaginal flora was normal in 157 (75.8%) and pathological in 50 (24.1%) women with ASC. In the ASC subgroup, the highest proportion of physiological vaginal flora was observed in 151 patients (77.4%) with ASC-US, in comparison to 44 (22.6%) with ASC-H, in which the percentage of women with normal or abnormal flora was the same (50%vs 50%). This difference was statistically significant. In case of AGC, vaginal culture was physiological in 23 (65.7%) women, and in 12 (34.3%) abnormal vaginal flora with features of the inflammation. The statistically significant influence of abnormal vaginal flora on the presence of atypical endometrial and endocervical cells was not observed. Conclusions: We did not observed any influence of abnormal vaginal flora on the presence, regression and progression of ASC and AGC .

Article available in PDF format

View PDF Download PDF file