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Vol 81, No 6 (2010)
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Influence of oncological treatment on fertility of women and pregnancy outcome

Anna Markowska, Monika Pawłowska, Janina Markowska, Maria Litwiniuk, Radosław Mądry, Darah Dilmaghani-Tabriz
Ginekol Pol 2010;81(6).

open access

Vol 81, No 6 (2010)
ARTICLES

Abstract

Abstract Advances in cancer treatment of young patients have resulted in markedly improved survival rates and quality of life. However, infertility remains to be one of adverse effects of anticancer therapy. Female patients who receive high-dose abdominal and/or pelvic irradiation or chemotherapy based on alkylating agents are at highest risk of developing ovarian failure. Among women whose fertility was not impaired during oncologic treatment, there is a significantly increased number of premature labors. High-dose irradiation also predisposes to low-birthweight infants. Neither chemotherapy nor radiotherapy increase a risk of congenital malformations.

Abstract

Abstract Advances in cancer treatment of young patients have resulted in markedly improved survival rates and quality of life. However, infertility remains to be one of adverse effects of anticancer therapy. Female patients who receive high-dose abdominal and/or pelvic irradiation or chemotherapy based on alkylating agents are at highest risk of developing ovarian failure. Among women whose fertility was not impaired during oncologic treatment, there is a significantly increased number of premature labors. High-dose irradiation also predisposes to low-birthweight infants. Neither chemotherapy nor radiotherapy increase a risk of congenital malformations.

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Keywords

inertility, oncologic treatment

About this article
Title

Influence of oncological treatment on fertility of women and pregnancy outcome

Journal

Ginekologia Polska

Issue

Vol 81, No 6 (2010)

Page views

577

Article views/downloads

4023

Bibliographic record

Ginekol Pol 2010;81(6).

Keywords

inertility
oncologic treatment

Authors

Anna Markowska
Monika Pawłowska
Janina Markowska
Maria Litwiniuk
Radosław Mądry
Darah Dilmaghani-Tabriz

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