Vol 81, No 7 (2010)
ARTICLES
Recombinant factor VIIa for treatment of postpartum hemorrhage due to uterine atony
Grażyna Michalska-Krzanowska
Vol 81, No 7 (2010)
ARTICLES
Abstract
Abstract Background: Obstetric hemorrhage is a life-threatening situation for every mother and child. NovoSeven is a recombinant, activated factor VII which may be useful in the treatment of uncontrollable hemorrhage. It accelerates hemostasis by direct activation of the factor X. Material and methods: The author presents her own experience with administration of NovoSeven at the Intensive Care Unit, Medical University Szczecin in the treatment of bleedings after standard methods failure. NovoSeven was given to patients in postpartum hemorrhage due to uterine atony, who did not present any signs of haemostatic disorders. Results: In all presented cases, bleeding symptoms abated and hemodynamic stabilization was obtained shortly after the drug administration. Conclusion: NovoSeven is a very effective agent in the treatment of postpartum hemorrhage.
Abstract
Abstract Background: Obstetric hemorrhage is a life-threatening situation for every mother and child. NovoSeven is a recombinant, activated factor VII which may be useful in the treatment of uncontrollable hemorrhage. It accelerates hemostasis by direct activation of the factor X. Material and methods: The author presents her own experience with administration of NovoSeven at the Intensive Care Unit, Medical University Szczecin in the treatment of bleedings after standard methods failure. NovoSeven was given to patients in postpartum hemorrhage due to uterine atony, who did not present any signs of haemostatic disorders. Results: In all presented cases, bleeding symptoms abated and hemodynamic stabilization was obtained shortly after the drug administration. Conclusion: NovoSeven is a very effective agent in the treatment of postpartum hemorrhage.
Keywords
postpartum hemorrhage, uterine atony, recombinant activated factor VII, Haemostasis
Title
Recombinant factor VIIa for treatment of postpartum hemorrhage due to uterine atony
Journal
Ginekologia Polska
Issue
Vol 81, No 7 (2010)
Page views
542
Article views/downloads
1680
Bibliographic record
Ginekol Pol 2010;81(7).
Keywords
postpartum hemorrhage
uterine atony
recombinant activated factor VII
Haemostasis
Authors
Grażyna Michalska-Krzanowska
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