Pathogenesis of liver diseases associated with pregnancy

Abstract

Summary Liver diseases in pregnancy constitute substantial clinical problem. Liver diseases occurring only during pregnancy, include: intrahepatic cholestasis of pregnancy, acute fatty liver of pregnancy, HELLP syndrome, pre-eclampsia and eclampsia. They can be associated with significant maternal and fetal morbidity and mortality. The following article explores the pathogenesis, the clinical features, risk factors and management of above listed disorders. Early diagnosis and immediate decisions are essential for maternal and fetal survival.