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Vol 81, No 11 (2010)
ARTICLES
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Comparative analysis of abnormal Pap smear and the results of histopathological examination of specimens from the cervix of the Programme in-depth Diagnosis Cervical Cancer conducted at the of Operational Gynecology Department ICZMP in Lodz

Bartosz Kulig, Stanisław Łukaszek, Aleksandra Brucka, Andrzej Kałużyński, Anna Kamer-Bartosińska, Krzysztof Szyłło
Ginekol Pol 2010;81(11).

open access

Vol 81, No 11 (2010)
ARTICLES

Abstract

Abstract Introduction: Cervical Cancer Screening Program has been operational in Poland for over four years. Colposcopy and guided biopsy methods constitute an essential part of population-based screening, enable stating right diagnosis and planning treatment procedures. Aim: The aim of the following study was to analyse the diagnostic acuity of cyto- and histopathological examination. Results: We examined 510 patients with the following result of cytological smear : ASCUS – 265 women (51.96%), LSIL – 167 cases (35.75%), HSIL – 78 women (15.29%). Complete agreement between cytological smear and guided biopsy histopathology was observed among 81.13% cases of ASCUS, in 88.02% of women with LSIL and in 76.92% cases with the diagnosis of HSIL. As with cytology-biopsy comparisons, discordant cases were significantly more frequent in the group with stated HSIL than among patients with the diagnosis of ASCUS or LSIL (p<0.001). Conclusions: 1. High cyto- histopathological accordance (82%) has been obtained, what is comparable with the data in literature. 2. The highest cyto- histopathological compatibility was obtained in the group of patients with LSIL – over 88%, and the lowest in the group of patients with HSIL – less than 77%. 3. Failure to confirm the histopathological diagnosis of cytological HSIL requires further molecular and morphological evaluation.

Abstract

Abstract Introduction: Cervical Cancer Screening Program has been operational in Poland for over four years. Colposcopy and guided biopsy methods constitute an essential part of population-based screening, enable stating right diagnosis and planning treatment procedures. Aim: The aim of the following study was to analyse the diagnostic acuity of cyto- and histopathological examination. Results: We examined 510 patients with the following result of cytological smear : ASCUS – 265 women (51.96%), LSIL – 167 cases (35.75%), HSIL – 78 women (15.29%). Complete agreement between cytological smear and guided biopsy histopathology was observed among 81.13% cases of ASCUS, in 88.02% of women with LSIL and in 76.92% cases with the diagnosis of HSIL. As with cytology-biopsy comparisons, discordant cases were significantly more frequent in the group with stated HSIL than among patients with the diagnosis of ASCUS or LSIL (p<0.001). Conclusions: 1. High cyto- histopathological accordance (82%) has been obtained, what is comparable with the data in literature. 2. The highest cyto- histopathological compatibility was obtained in the group of patients with LSIL – over 88%, and the lowest in the group of patients with HSIL – less than 77%. 3. Failure to confirm the histopathological diagnosis of cytological HSIL requires further molecular and morphological evaluation.
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Keywords

colposcopy, cervical smears, cervical cancer

About this article
Title

Comparative analysis of abnormal Pap smear and the results of histopathological examination of specimens from the cervix of the Programme in-depth Diagnosis Cervical Cancer conducted at the of Operational Gynecology Department ICZMP in Lodz

Journal

Ginekologia Polska

Issue

Vol 81, No 11 (2010)

Bibliographic record

Ginekol Pol 2010;81(11).

Keywords

colposcopy
cervical smears
cervical cancer

Authors

Bartosz Kulig
Stanisław Łukaszek
Aleksandra Brucka
Andrzej Kałużyński
Anna Kamer-Bartosińska
Krzysztof Szyłło

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