Vol 81, No 12 (2010)
ARTICLES
Total oxidative status of peritoneal fluid in women with endometriosis
Grzegorz Polak, Jan Kotarski
Vol 81, No 12 (2010)
ARTICLES
Abstract
Abstract Pathophysiology of endometriosis remains enigmatic despite extensive investigations. Accumulating data suggest that oxidative stress in the peritoneal cavity may be implicated in the pathogenesis of endometriosis. Aim: The aim of our study was to evaluate the oxidative status of peritoneal fluid (PF) in women with and without endometriosis. Material and methods: Sixty-five women participated in the study. 40 women with endometriosis constituted the study group and 25 patients with functional follicle ovarian cysts comprised the reference group. Total oxidative status of PF was determined using a commercially available colorimetric assay kit (Immundiagnostic AG, Cat. nr. KC5100). Results: Women with endometriosis had significantly higher PF oxidative status compared to women with follicle ovarian cysts. No significant difference in the peritoneal oxidative status was found between patients with stage I/II endometriosis, and women with stage III/IV endometriotic disease. Conclusions: Disrupted oxidative status in the peritoneal cavity of women with endometriosis plays a role in the pathogenesis of the disease.
Abstract
Abstract Pathophysiology of endometriosis remains enigmatic despite extensive investigations. Accumulating data suggest that oxidative stress in the peritoneal cavity may be implicated in the pathogenesis of endometriosis. Aim: The aim of our study was to evaluate the oxidative status of peritoneal fluid (PF) in women with and without endometriosis. Material and methods: Sixty-five women participated in the study. 40 women with endometriosis constituted the study group and 25 patients with functional follicle ovarian cysts comprised the reference group. Total oxidative status of PF was determined using a commercially available colorimetric assay kit (Immundiagnostic AG, Cat. nr. KC5100). Results: Women with endometriosis had significantly higher PF oxidative status compared to women with follicle ovarian cysts. No significant difference in the peritoneal oxidative status was found between patients with stage I/II endometriosis, and women with stage III/IV endometriotic disease. Conclusions: Disrupted oxidative status in the peritoneal cavity of women with endometriosis plays a role in the pathogenesis of the disease.
Keywords
endometriosis, Oxidative status, peritoneal fluid
Title
Total oxidative status of peritoneal fluid in women with endometriosis
Journal
Ginekologia Polska
Issue
Vol 81, No 12 (2010)
Page views
646
Article views/downloads
1158
Bibliographic record
Ginekol Pol 2010;81(12).
Keywords
endometriosis
Oxidative status
peritoneal fluid
Authors
Grzegorz Polak
Jan Kotarski
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