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Vol 82, No 4 (2011)
ARTICLES
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A case of antiphospholipid syndrome in course of pregnancy and puerperium with lupus-like disease suspicion

Anna Lorenc, Agnieszka Seremak-Mrozikiewicz, Krzysztof Drews, Paweł Ratajczak, Mariusz Puszczewicz
Ginekol Pol 2011;82(4).

open access

Vol 82, No 4 (2011)
ARTICLES

Abstract

Summary The antiphospholipid syndrome (APS) is a systemic non-inflammatory and autoimmune connective tissue disease. ASP is characterized by formation of autoantibodies against cell membrane phospholipids which act as procaogulation factors. Association with recurrent pregnancy loss, intrauterine growth retardation, preeclampsia and placenta ablation makes ASP a serious perinatologic problem. The primary form can evaluate into lupus-like disease or fullsymptomatic lupus erythematosus, both usually preceded by acute form of APS. In pregnant women this situation may present considerable diagnostic problems. The aim of this work was to present a patient with acute primary antiphospholipid syndrome during pregnancy and puerperium, which subsequently was diagnosed as systemic lupus erythematosus flare. Such progression is rare and, despite several previous reports, requires extensive explanations and research.

Abstract

Summary The antiphospholipid syndrome (APS) is a systemic non-inflammatory and autoimmune connective tissue disease. ASP is characterized by formation of autoantibodies against cell membrane phospholipids which act as procaogulation factors. Association with recurrent pregnancy loss, intrauterine growth retardation, preeclampsia and placenta ablation makes ASP a serious perinatologic problem. The primary form can evaluate into lupus-like disease or fullsymptomatic lupus erythematosus, both usually preceded by acute form of APS. In pregnant women this situation may present considerable diagnostic problems. The aim of this work was to present a patient with acute primary antiphospholipid syndrome during pregnancy and puerperium, which subsequently was diagnosed as systemic lupus erythematosus flare. Such progression is rare and, despite several previous reports, requires extensive explanations and research.
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Keywords

pregnancy, antiphospholipid syndrome, lupus-like diseases, Systemic lupus erythematosus

About this article
Title

A case of antiphospholipid syndrome in course of pregnancy and puerperium with lupus-like disease suspicion

Journal

Ginekologia Polska

Issue

Vol 82, No 4 (2011)

Bibliographic record

Ginekol Pol 2011;82(4).

Keywords

pregnancy
antiphospholipid syndrome
lupus-like diseases
Systemic lupus erythematosus

Authors

Anna Lorenc
Agnieszka Seremak-Mrozikiewicz
Krzysztof Drews
Paweł Ratajczak
Mariusz Puszczewicz

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