open access

Vol 82, No 7 (2011)
ARTICLES
Get Citation

Comparison of VEGF, IL-8 and β-FGF concentrations in the serum and ascites of patients with ovarian cancer

Paweł Sadłecki, Małgorzata Walentowicz-Sadłecka, Wiesław Szymański, Marek Grabiec
Ginekol Pol 2011;82(7).

open access

Vol 82, No 7 (2011)
ARTICLES

Abstract

Abstract Epithelial ovarian cancer is the leading cause of cancer death from gynecological malignancies. Angiogenesis is considered essential for tumor growth and the development of metastases. VEGF, IL−8, β-FGF are potent angiostimulatory molecules and their expression has been demonstrated in many solid tumors, including ovarian cancer. The aim of this study was to compare the levels of VEGF, IL−8 and β-FGF in the serum and ascites of patients with ovarian cancer. VEGF, IL−8, β-FGF concentrations were measured by ELISA (Quantikine R&D). The median VEGF, IL−8 and β-FGF levels were significantly higher in the ascites than sera of ovarian cancer patient. VEGF, IL−8, β-FGF levels in ascites might be regarded as an additional tool in the diagnosis of ovarian cancer.

Abstract

Abstract Epithelial ovarian cancer is the leading cause of cancer death from gynecological malignancies. Angiogenesis is considered essential for tumor growth and the development of metastases. VEGF, IL−8, β-FGF are potent angiostimulatory molecules and their expression has been demonstrated in many solid tumors, including ovarian cancer. The aim of this study was to compare the levels of VEGF, IL−8 and β-FGF in the serum and ascites of patients with ovarian cancer. VEGF, IL−8, β-FGF concentrations were measured by ELISA (Quantikine R&D). The median VEGF, IL−8 and β-FGF levels were significantly higher in the ascites than sera of ovarian cancer patient. VEGF, IL−8, β-FGF levels in ascites might be regarded as an additional tool in the diagnosis of ovarian cancer.
Get Citation

Keywords

ovarian cancer, angiogenesis

About this article
Title

Comparison of VEGF, IL-8 and β-FGF concentrations in the serum and ascites of patients with ovarian cancer

Journal

Ginekologia Polska

Issue

Vol 82, No 7 (2011)

Bibliographic record

Ginekol Pol 2011;82(7).

Keywords

ovarian cancer
angiogenesis

Authors

Paweł Sadłecki
Małgorzata Walentowicz-Sadłecka
Wiesław Szymański
Marek Grabiec

Regulations

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk
tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl