The diagnostic value of cytology and colposcopy in women with cervical intraepithelial neoplasia

Abstract

Abstract Objectives: The aim of this study was to determine the diagnostic value of cytology and colposcopy in women with CIN. Material and methods: The study involved 687 women with histologically confirmed CIN. The colposcopic images were recorded and archived, followed by computer analysis. Pap smears were evaluated according to the Bethesda system. Statistical analysis was performed with Statistica Pl ver. 6,0 software. Results: The Pap smears had a sensitivity of 58,02% and 63,28% specificity in the diagnosis of CIN. Positive predictive value (PPV) for cytology was estimated at 75,38% and negative predictive value (NPV) at 43,75%. The study showed 89,21% sensitivity and 98,87% specificity of colposcopy in the diagnosis of CIN. The positive predictive value (PPV) for colposcopy was estimated at 99,35% and negative predictive value (NPV) at 82,55 %. Conclusions: 1. Diagnostic value of the Pap smears in the diagnosis of cervical intraepithelial neoplasia (CIN) is limited. 2. Colposcopy has a high sensitivity and specificity in the diagnosis of CIN.