Vol 82, No 9 (2011)

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Two histologically different tumours in a neonate born from an assisted reproductive technology pregnancy

Halina Konefał, Jarosław Peregud-Pogorzelski, Grażyna Hnatyszyn, Viloetta Posio, Maria Stepaniuk, Andrzej Kram, Maria Beata Czeszyńska
Ginekol Pol 2011;82(9).


The first case of a female neonate born from an in vitro fertilization with embryo transfer (IVF-ET) and intracytoplasmic sperm injection (ICSI) (IVF-ET (ICSI) with two histologically different tumours (craniopharyngioma and hepatoblastoma) is described. Anti-neoplasmatic therapy was abandoned due to the significant extent of the disease (craniopharyngioma, 15×12 cm in diameter with active internal hydrocephalus; and right liver lobe hepatoblastoma, 5 cm in diameter) and the severely impaired general condition of the neonate. The neonate died on the 30th day of life due to cerebellar and brainstem herniation, followed by circulatory and respiratory failure.

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