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Vol 82, No 12 (2011)
ARTICLES
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Antibiotic resistance of Gardnerella vaginalis isolated from cases of becterial vaginosis

Anna Tomusiak, Magdalena Heczko, Piotr Bogumił
Ginekol Pol 2011;82(12).

open access

Vol 82, No 12 (2011)
ARTICLES

Abstract

Summary Introduction: Gardnerella vaginalis is one of the dominant etiological factors related to bacterial vaginosis. Literature offers a growing number of reports revealing there appear Gardnerella vaginalis strains increasingly resistant to metronidazole. Objectives: The aim of this study was to determine the susceptibility of Gardnerella vaginalis strains isolated from women with bacterial vaginosis to metronidazole, clindamycin and amoxicillin/clavulanic acid. Material and methods: The investigation was performed on collection of 67 Gardnerella vaginalis strains isolated from the group of 604 women participating in the study. Antibiotic sensitivity of strains was verified by E-test method (BioMerieux). Interpretation of results was performed in accordance with EUCAST criteria. Results: All tested strains, apart from one, were sensitive to clindamycin and amoxicillin/clavulanic acid. The results of susceptibility test to metronidazole indicated that 68,7% (46 out of 67 strains) were resistant to this antibiotic, while all of them were sensitive to both clindamycin and amoxicillin/clavulanic acid. Conclusions: Near future may bring the need to change the treatment regimen of bacterial vaginosis.

Abstract

Summary Introduction: Gardnerella vaginalis is one of the dominant etiological factors related to bacterial vaginosis. Literature offers a growing number of reports revealing there appear Gardnerella vaginalis strains increasingly resistant to metronidazole. Objectives: The aim of this study was to determine the susceptibility of Gardnerella vaginalis strains isolated from women with bacterial vaginosis to metronidazole, clindamycin and amoxicillin/clavulanic acid. Material and methods: The investigation was performed on collection of 67 Gardnerella vaginalis strains isolated from the group of 604 women participating in the study. Antibiotic sensitivity of strains was verified by E-test method (BioMerieux). Interpretation of results was performed in accordance with EUCAST criteria. Results: All tested strains, apart from one, were sensitive to clindamycin and amoxicillin/clavulanic acid. The results of susceptibility test to metronidazole indicated that 68,7% (46 out of 67 strains) were resistant to this antibiotic, while all of them were sensitive to both clindamycin and amoxicillin/clavulanic acid. Conclusions: Near future may bring the need to change the treatment regimen of bacterial vaginosis.
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Keywords

Gardnerella vaginalis, antibiotic susceptibility, bacterial vaginosis

About this article
Title

Antibiotic resistance of Gardnerella vaginalis isolated from cases of becterial vaginosis

Journal

Ginekologia Polska

Issue

Vol 82, No 12 (2011)

Bibliographic record

Ginekol Pol 2011;82(12).

Keywords

Gardnerella vaginalis
antibiotic susceptibility
bacterial vaginosis

Authors

Anna Tomusiak
Magdalena Heczko
Piotr Bogumił

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