Body mass changes during pregnancy and concentration of insulin and neuropeptide Y in women with regard to the BMI

Abstract

Summary Introduction: Obesity poses a serious problem to human population as it increases the risk of diabetes, hypertension, metabolic syndrome. In pregnancy, obesity increases the frequency of its complications. Aim: The main aim of the study was to estimate the increase of body mass and insulin and neuropeptide Y concentrations in pregnant women. Material and methods: The changes of body mass and BMI in women before pregnancy and before delivery and the concentrations of insulin and neuropeptide Y in blood were estimated. Results. The increase of body mass and BMI during the pregnancy period was higher in the group with high body mass and I stage obesity and increase of insulin concentration depended on increase of the body mass. Higher concentration of NPY was found in the group of women with normal body mass and obese if compared to stages II and III of obesity. No correlation between insulin increase and concentration of NPY was found. Conclusions: In most pregnant women body mass gain is excessive and leads to obesity of different stages. Insulin concentration increases as BMI increases. Neuropeptide Y concentration in the obese women group was lower than in the normal weight group.