open access

Vol 83, No 1 (2012)
ARTICLES
Get Citation

Clinical and histopathological factors in patients with cervical cancer allowing to identify candidates for less radical surgery

Małgorzata Figat, Kamil Zalewski, Anna Dańska-Bidzińska, Jakub Rzepka, Piotr Sobiczewski, Mariusz Gujski, Mariusz Bidziński
Ginekol Pol 2012;83(1).

open access

Vol 83, No 1 (2012)
ARTICLES

Abstract

Objective: To determine clinical and histopathological factors in patients with cervical cancer tumors smaller than 2cm in order to identify those who could be operated less extensively with preservation of reproductive organs and lower morbidity. Material and methods: We retrospectively reviewed the records of patients with cervical cancer and a maximum tumor of 2cm in diameter who were qualified for primary surgery in the years 2001-2007 at the Department of Gynecologic Oncology, Cancer Center in Warsaw. Results: From the group of 110 operated patients, 96 were included into the study. Within the analyzed group the infiltration of the parametrium was found in 4 women (4.2%). All of them had squamous cell cancer; stage IB, grade G3. One patient had a tumor 1.5cm in diameter and 3 patients had tumors up to 2cm in diameter. The involvement of lymph nodes was observed in 3 patients with squamous cell carcinoma: in one case the tumor was intermediate grade (G2) and in two cases low grade (G3). The lymph nodes were involved only in patients with tumors greater than 0.5cm. The lymph vascular space invasion was found in 14 patients (14.7%): in 12 with squamous cell cancer and in 2 with adenocarcinoma. The diameter of the tumor was 0.5-1cm in 4 women, 1-1.4cm in 3 women and 1.5-2cm in the majority (7 women accounted for 29% of all patients in that group). No infiltration of the blood vessels could be seen in all 30 women with tumors smaller than 0.5cm. We found a statistically significant relationship between the size of the tumor and the incidence of lymph vascular space invasion (p=0.024). Conclusion: In selective cases fertility organ preserving surgery is possible and safe. In the group of patients with tumor less than 5 mm in diameter no parametrium involvement or lymph metastases were observed. In such situation cervical conisation can be justified. In well-differentiated (G1) tumors less than 2 cm in diameter, less radical surgical procedures can also be performed because no treatment failure has been observed .

Abstract

Objective: To determine clinical and histopathological factors in patients with cervical cancer tumors smaller than 2cm in order to identify those who could be operated less extensively with preservation of reproductive organs and lower morbidity. Material and methods: We retrospectively reviewed the records of patients with cervical cancer and a maximum tumor of 2cm in diameter who were qualified for primary surgery in the years 2001-2007 at the Department of Gynecologic Oncology, Cancer Center in Warsaw. Results: From the group of 110 operated patients, 96 were included into the study. Within the analyzed group the infiltration of the parametrium was found in 4 women (4.2%). All of them had squamous cell cancer; stage IB, grade G3. One patient had a tumor 1.5cm in diameter and 3 patients had tumors up to 2cm in diameter. The involvement of lymph nodes was observed in 3 patients with squamous cell carcinoma: in one case the tumor was intermediate grade (G2) and in two cases low grade (G3). The lymph nodes were involved only in patients with tumors greater than 0.5cm. The lymph vascular space invasion was found in 14 patients (14.7%): in 12 with squamous cell cancer and in 2 with adenocarcinoma. The diameter of the tumor was 0.5-1cm in 4 women, 1-1.4cm in 3 women and 1.5-2cm in the majority (7 women accounted for 29% of all patients in that group). No infiltration of the blood vessels could be seen in all 30 women with tumors smaller than 0.5cm. We found a statistically significant relationship between the size of the tumor and the incidence of lymph vascular space invasion (p=0.024). Conclusion: In selective cases fertility organ preserving surgery is possible and safe. In the group of patients with tumor less than 5 mm in diameter no parametrium involvement or lymph metastases were observed. In such situation cervical conisation can be justified. In well-differentiated (G1) tumors less than 2 cm in diameter, less radical surgical procedures can also be performed because no treatment failure has been observed .
Get Citation

Keywords

cervical cancer, fertility preservation, treatment

About this article
Title

Clinical and histopathological factors in patients with cervical cancer allowing to identify candidates for less radical surgery

Journal

Ginekologia Polska

Issue

Vol 83, No 1 (2012)

Page views

551

Article views/downloads

654

Bibliographic record

Ginekol Pol 2012;83(1).

Keywords

cervical cancer
fertility preservation
treatment

Authors

Małgorzata Figat
Kamil Zalewski
Anna Dańska-Bidzińska
Jakub Rzepka
Piotr Sobiczewski
Mariusz Gujski
Mariusz Bidziński

Regulations

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By VM Media Group sp. z o.o., ul. Świętokrzyska 73, 80–180 Gdańsk
tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl