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Vol 83, No 5 (2012)
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Chorionic Villus Sampling in cytogenetic analysis – disadvantages and advantages

Agnieszka Gnyś-Wiercioch, Renata Bloch, Barbara Grolik, Jolanta Hadaś, Agnieszka Kania, Mariola Szołtysik-Szot, Henryka Sodowska
Ginekol Pol 2012;83(5).

open access

Vol 83, No 5 (2012)
ARTICLES

Abstract

Chorionic villus sampling is used in prenatal diagnosis, enabling to detect fetal genetic abnormalities. Its advantages include the possibility of performing the procedure during the first trimester of pregnancy, relatively fast result, risk of miscarriage comparable to that in case of amniocentesis. The disadvantages of this method are: difficult cytogenetic analysis, the possibility of contamination with maternal cells and the risk of mosaicism. There should always be a valid indication to perform the CVS procedure.

Abstract

Chorionic villus sampling is used in prenatal diagnosis, enabling to detect fetal genetic abnormalities. Its advantages include the possibility of performing the procedure during the first trimester of pregnancy, relatively fast result, risk of miscarriage comparable to that in case of amniocentesis. The disadvantages of this method are: difficult cytogenetic analysis, the possibility of contamination with maternal cells and the risk of mosaicism. There should always be a valid indication to perform the CVS procedure.

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Keywords

prenatal diagnosis, Chorionic Villus Sampling, mosaicism, confined placental mosaicism

About this article
Title

Chorionic Villus Sampling in cytogenetic analysis – disadvantages and advantages

Journal

Ginekologia Polska

Issue

Vol 83, No 5 (2012)

Page views

764

Article views/downloads

6314

Bibliographic record

Ginekol Pol 2012;83(5).

Keywords

prenatal diagnosis
Chorionic Villus Sampling
mosaicism
confined placental mosaicism

Authors

Agnieszka Gnyś-Wiercioch
Renata Bloch
Barbara Grolik
Jolanta Hadaś
Agnieszka Kania
Mariola Szołtysik-Szot
Henryka Sodowska

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