Features of pubescence in patients with pure gonadal dysgenesis in the course of a hormonally active tumor – case report

Abstract

Germ cell tumors are the most frequent ovarian neoplasms among girls and young women under the age of 25. Female patients with gonadal dysgenesis are at higher risk of germ cell tumors. Two cases of women with pure gonadal dysgenesis were described. A hormonally active tumor, secreting estrogens, caused the development of sexual features and genital tract bleeding what imitated premature puberty. It needs to be emphasized that the presence of sexual features does not exclude dysgenesis - a pathology that is connected with an increased risk of gonadal tumors - and that the ultrasound evaluation, during which the presence of follicles in gonads is evaluated, is essential..