open access

Vol 84, No 3 (2013)
ARTICLES
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Alteration of peripheral blood cells in tubal ectopic pregnancy

Abdulkadir Turgut, Muhammet Erdal Sak, Ali Ozier, Hatice Ender Soydinc, Talip Karacor, Talip Gul
DOI: 10.17772/gp/1562
·
Ginekol Pol 2013;84(3).

open access

Vol 84, No 3 (2013)
ARTICLES

Abstract

Objectives: To investigate whether mean platelet volumes and leukocyte counts are altered significantly in patients with tubal ectopic pregnancy (TEP). Materials and Methods: Retrospective analysis of mean platelet volumes and leukocyte counts of 138 TEP patients, diagnosed between 2005 and 2012, and the control group consisting of 72 pregnants was performed. Patients with TEP were further subdivided into 2 subgroups composed of 72 ruptured and 66 non-ruptured cases. Statistical analysis was performed using the Kruskal-Wallis and the Mann-Whitney U tests. Results: Mean platelet volume was found to be larger in patients with TEP (whether ruptured or non-ruptured) when compared to controls (p=0.007). However, no significant difference could be observed between the ruptured or non-ruptured cases (p=0.89). With respect to leukocytosis, the TEP group with tubal rupture had significantly higher white blood cell numbers when compared to the non-ruptured TEP and the control groups (p=0.022 and p<0.001, respectively). Conclusions: Mean platelet volume seems to be higher in ectopic pregnancy and this finding evokes a possible role of increased platelet activity in the pathophysiology. Leukocytosis may occur more apparently in EP cases with tubal rupture. However, further prospective, controlled and with a larger sample size studies must be conducted to find clues on the correlation between the clinical entities and laboratory findings.

Abstract

Objectives: To investigate whether mean platelet volumes and leukocyte counts are altered significantly in patients with tubal ectopic pregnancy (TEP). Materials and Methods: Retrospective analysis of mean platelet volumes and leukocyte counts of 138 TEP patients, diagnosed between 2005 and 2012, and the control group consisting of 72 pregnants was performed. Patients with TEP were further subdivided into 2 subgroups composed of 72 ruptured and 66 non-ruptured cases. Statistical analysis was performed using the Kruskal-Wallis and the Mann-Whitney U tests. Results: Mean platelet volume was found to be larger in patients with TEP (whether ruptured or non-ruptured) when compared to controls (p=0.007). However, no significant difference could be observed between the ruptured or non-ruptured cases (p=0.89). With respect to leukocytosis, the TEP group with tubal rupture had significantly higher white blood cell numbers when compared to the non-ruptured TEP and the control groups (p=0.022 and p<0.001, respectively). Conclusions: Mean platelet volume seems to be higher in ectopic pregnancy and this finding evokes a possible role of increased platelet activity in the pathophysiology. Leukocytosis may occur more apparently in EP cases with tubal rupture. However, further prospective, controlled and with a larger sample size studies must be conducted to find clues on the correlation between the clinical entities and laboratory findings.
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Keywords

ectopic pregnancy, Tubal Pregnancy, mean platelet volume, leukocyte count

About this article
Title

Alteration of peripheral blood cells in tubal ectopic pregnancy

Journal

Ginekologia Polska

Issue

Vol 84, No 3 (2013)

DOI

10.17772/gp/1562

Bibliographic record

Ginekol Pol 2013;84(3).

Keywords

ectopic pregnancy
Tubal Pregnancy
mean platelet volume
leukocyte count

Authors

Abdulkadir Turgut
Muhammet Erdal Sak
Ali Ozier
Hatice Ender Soydinc
Talip Karacor
Talip Gul

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