Vol 84, No 6 (2013)
ARTICLES
The role of vitamin D deficiency in the etiology of polycystic ovary syndrome disorders
Maria Brzozowska, Agata Karowicz-Bilińska
DOI: 10.17772/gp/1604
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Ginekol Pol 2013;84(6).
Vol 84, No 6 (2013)
ARTICLES
Abstract
Vitamin D deficiency, connected with insufficient production in the skin and limited alimentation delivery, disrupts the function of all systems of the body and increases the risk of chronic diseases. Many studies have reported associations between low serum 25-hydroxyvitamin D [25(OH)D] level and symptoms of the polycystic ovary syndrome (PCOS) – insulin resistance, hirsutism, and infertility associated with both, ovulatory disorders and abnormal endometrial receptivity. The beneficial effects of vitamin D supplementation on insulin resistance, ovarian follicles maturation, ovulation and menstrual regularity were confirmed. Due to limited evidence, the additional randomized trials are required to establish the correct dose of vitamin D and confirm the effectiveness of vitamin D treatment in PCOS disorders. However, it seems evident that correct supplementation of vitamin D is beneficial in the management of women with PCOS and low 25(OH)D serum levels, and that it could be helpful in improving the effects of PCOS treatment.
Abstract
Vitamin D deficiency, connected with insufficient production in the skin and limited alimentation delivery, disrupts the function of all systems of the body and increases the risk of chronic diseases. Many studies have reported associations between low serum 25-hydroxyvitamin D [25(OH)D] level and symptoms of the polycystic ovary syndrome (PCOS) – insulin resistance, hirsutism, and infertility associated with both, ovulatory disorders and abnormal endometrial receptivity. The beneficial effects of vitamin D supplementation on insulin resistance, ovarian follicles maturation, ovulation and menstrual regularity were confirmed. Due to limited evidence, the additional randomized trials are required to establish the correct dose of vitamin D and confirm the effectiveness of vitamin D treatment in PCOS disorders. However, it seems evident that correct supplementation of vitamin D is beneficial in the management of women with PCOS and low 25(OH)D serum levels, and that it could be helpful in improving the effects of PCOS treatment.
Keywords
vitamin D, polycystic ovary syndrome, insulin resistance, infertility
Title
The role of vitamin D deficiency in the etiology of polycystic ovary syndrome disorders
Journal
Ginekologia Polska
Issue
Vol 84, No 6 (2013)
Page views
3145
Article views/downloads
10000
DOI
10.17772/gp/1604
Bibliographic record
Ginekol Pol 2013;84(6).
Keywords
vitamin D
polycystic ovary syndrome
insulin resistance
infertility
Authors
Maria Brzozowska
Agata Karowicz-Bilińska
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