open access

Vol 84, No 9 (2013)
ARTICLES
Get Citation

SUVmax measured by 18F FDG PET/CT in the primary tumor in relations to clinical and pathological features of endometrial cancer

Małgorzata Walentowicz-Sadłecka, Paweł Sadłecki, Bogdan Małecki, Paweł Walentowicz, Andrzej Marszałek, Piotr Domaracki, Marek Grabiec
DOI: 10.17772/gp/1634
·
Ginekol Pol 2013;84(9).

open access

Vol 84, No 9 (2013)
ARTICLES

Abstract

The aim: The aim of the study was to determine the value of SUVmax by PET/CT measured before surgery with special focus on FIGO stage, myometrial invasion, grading and risk stratification. Methods: A total of 90 women, aged 37-84 (mean 65.1± 9.5) with endometrial cancer (FIGO I and II) underwent 18F FDG PET/CT imaging before surgery. SUVmax of the primary tumor was assessed and compared with histological prognostic factors (FIGO stage, grading, myometrial invasion, risk group). Results: The mean SUVmax in the study group was 13.95 ± 5.49. SUVmax was significantly higher with high FIGO stage (p=0,0009), deep myometrial invasion (p=0.0005), high grade (p=0.0331) and high risk tumors (0.0007). Patients with the poor prognosis had significantly higher SUVmax values. Conclusions: The preoperative SUVmax measurements of the primary tumor of endometrial cancer may give additional clinical and prognostic information about risk factors and poor prognosis. High value of SUVmax might be useful in making noninvasive diagnoses and deciding the appropriate therapeutic strategy for patients with endometrial cancer. However, there is not enough evidence that it could in fact replace surgical staging.

Abstract

The aim: The aim of the study was to determine the value of SUVmax by PET/CT measured before surgery with special focus on FIGO stage, myometrial invasion, grading and risk stratification. Methods: A total of 90 women, aged 37-84 (mean 65.1± 9.5) with endometrial cancer (FIGO I and II) underwent 18F FDG PET/CT imaging before surgery. SUVmax of the primary tumor was assessed and compared with histological prognostic factors (FIGO stage, grading, myometrial invasion, risk group). Results: The mean SUVmax in the study group was 13.95 ± 5.49. SUVmax was significantly higher with high FIGO stage (p=0,0009), deep myometrial invasion (p=0.0005), high grade (p=0.0331) and high risk tumors (0.0007). Patients with the poor prognosis had significantly higher SUVmax values. Conclusions: The preoperative SUVmax measurements of the primary tumor of endometrial cancer may give additional clinical and prognostic information about risk factors and poor prognosis. High value of SUVmax might be useful in making noninvasive diagnoses and deciding the appropriate therapeutic strategy for patients with endometrial cancer. However, there is not enough evidence that it could in fact replace surgical staging.
Get Citation

Keywords

PET, CT, SUVmax, endometrial cancer

About this article
Title

SUVmax measured by 18F FDG PET/CT in the primary tumor in relations to clinical and pathological features of endometrial cancer

Journal

Ginekologia Polska

Issue

Vol 84, No 9 (2013)

DOI

10.17772/gp/1634

Bibliographic record

Ginekol Pol 2013;84(9).

Keywords

PET
CT
SUVmax
endometrial cancer

Authors

Małgorzata Walentowicz-Sadłecka
Paweł Sadłecki
Bogdan Małecki
Paweł Walentowicz
Andrzej Marszałek
Piotr Domaracki
Marek Grabiec

Regulations

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk
tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl