The role of inositol deficiency in the etiology of polycystic ovary syndrome disorders

Artur J. Jakimiuk; Jacek Szamatowicz

doi:10.17772/gp/1691

Vol 85, No 1 (2014)

ARTICLES

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The role of inositol deficiency in the etiology of polycystic ovary syndrome disorders

Artur J. Jakimiuk, Jacek Szamatowicz

DOI: 10.17772/gp/1691

Ginekol Pol 2014;85(1).

Vol 85, No 1 (2014)

ARTICLES

Abstract

Inositol acts as a second messenger in insulin signaling pathway. Literature data suggest inositol deficiency in insulin-resistant women with the polycystic ovary syndrome. Supplementation of myo-inisitol decreases insulin resistance as it works as an insulin sensitizing agent. The positive role of myo-inositol in the treatment of polycystic ovary syndrome has been of increased evidence recently. The present review presents the effects of myo-inositol on the ovarian, hormonal and metabolic parameters in women with PCOS.