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Vol 85, No 7 (2014)
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Metformin in pregnancy

Grzegorz Jakiel, Julia Bijok, Małgorzata Bińkowska
DOI: 10.17772/gp/1765
·
Ginekol Pol 2014;85(7).

open access

Vol 85, No 7 (2014)
ARTICLES

Abstract

Metformin is an oral insulin-sensitizing anti-diabetic drug. Polycystic ovary syndrome (PCOS) and gestational diabetes (GDM) are both associated with insulin resistance and hyperinsulinemia. Metformin can bring potential benefits in pregnant women due to its favorable metabolic effect. Nevertheless, there is a possibility of adverse effects on the fetus as metformin crosses the placenta. In this review we discuss safety and indications for metformin administration in pregnancy.

Abstract

Metformin is an oral insulin-sensitizing anti-diabetic drug. Polycystic ovary syndrome (PCOS) and gestational diabetes (GDM) are both associated with insulin resistance and hyperinsulinemia. Metformin can bring potential benefits in pregnant women due to its favorable metabolic effect. Nevertheless, there is a possibility of adverse effects on the fetus as metformin crosses the placenta. In this review we discuss safety and indications for metformin administration in pregnancy.

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Keywords

polycystic ovary syndrom, infertility, gestational diabetes

About this article
Title

Metformin in pregnancy

Journal

Ginekologia Polska

Issue

Vol 85, No 7 (2014)

Page views

3035

Article views/downloads

13284

DOI

10.17772/gp/1765

Bibliographic record

Ginekol Pol 2014;85(7).

Keywords

polycystic ovary syndrom
infertility
gestational diabetes

Authors

Grzegorz Jakiel
Julia Bijok
Małgorzata Bińkowska

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