Toxic epidermal necrolysis complicating
antibiotic treatment of puerperal endometritis:
a case report

Ondrej Simetka; Igor Michalec; Zdenka Nemeckova Crkvenjas; Hana Klosova; Lenka Janackova; Jaroslav Klat

Vol 86, No 4 (2015)

ARTICLES

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Toxic epidermal necrolysis complicating antibiotic treatment of puerperal endometritis: a case report

Ondrej Simetka, Igor Michalec, Zdenka Nemeckova Crkvenjas, Hana Klosova, Lenka Janackova, Jaroslav Klat

Ginekol Pol 2015;86(4).

Vol 86, No 4 (2015)

ARTICLES

Abstract

The aim of the study is to describe a case report of Lyell syndrome (toxic epidermal necrolysis) involving 63% of body surface which has been associated with antibiotic therapy of mild peurperal endometritis in woman 3 weeks postpartum. Lyell syndrome is a severe life-threatening condition developing due to idiosyncrazy (alergic reaction type IV), most commonly after administration of drugs. Incidence quoted in literature is around 1:1-2000000. Illness severity can be assessed using a SCORTEN scoring system, which predicts patient mortality based on seven independent factors. Lyell syndrome is a very rare but potentially lethal complication of antibiotic treatment.