open access

Vol 86, No 5 (2015)
ARTICLES
Get Citation

Polycystic ovary syndrome (PCOS) and gestational diabetes mellitus (GDM) risk

Tadeusz Issat, Małgorzata A. Nowicka, Artur J. Jakimiuk
DOI: 10.17772/gp/2429
·
Ginekol Pol 2015;86(5).

open access

Vol 86, No 5 (2015)
ARTICLES

Abstract

Gestational diabetes mellitus (GDM) is a common complication of pregnancy. In the course of pregnancy, elevated levels of hormones and other proteins having insulin-antagonistic effects lead to higher insulin resistance in peripheral tissues, followed by hyperinsulinemia. Risk factors for the development of GDM have been well-established. However, the debate whether polycystic ovary syndrome (PCOS) may predispose to GDM continues. Patients with PCOS are often affected by obesity, dyslipidemia, hyperinsulinemia ,and tissue-specific insulin resistance. Obesity occurs in 50% of the cases, while tissue-specific insulin resistance is observed in 20-40% of the affected patients. This paper aims at systematizing risk factors that could contribute to the development of GDM, as well as reviewing literature reports and analyses on the occurrence of a potential correlation.

Abstract

Gestational diabetes mellitus (GDM) is a common complication of pregnancy. In the course of pregnancy, elevated levels of hormones and other proteins having insulin-antagonistic effects lead to higher insulin resistance in peripheral tissues, followed by hyperinsulinemia. Risk factors for the development of GDM have been well-established. However, the debate whether polycystic ovary syndrome (PCOS) may predispose to GDM continues. Patients with PCOS are often affected by obesity, dyslipidemia, hyperinsulinemia ,and tissue-specific insulin resistance. Obesity occurs in 50% of the cases, while tissue-specific insulin resistance is observed in 20-40% of the affected patients. This paper aims at systematizing risk factors that could contribute to the development of GDM, as well as reviewing literature reports and analyses on the occurrence of a potential correlation.
Get Citation

Keywords

pregnancy / gestational diabetes mellitus / polycystic ovary syndromes /

About this article
Title

Polycystic ovary syndrome (PCOS) and gestational diabetes mellitus (GDM) risk

Journal

Ginekologia Polska

Issue

Vol 86, No 5 (2015)

DOI

10.17772/gp/2429

Bibliographic record

Ginekol Pol 2015;86(5).

Keywords

pregnancy / gestational diabetes mellitus / polycystic ovary syndromes /

Authors

Tadeusz Issat
Małgorzata A. Nowicka
Artur J. Jakimiuk

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk
tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl