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Vol 86, No 5 (2015)
ARTICLES
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Relation of platelet distribution width (PDW) and platelet crit (PCT) to preeclampsia

Atilla Karateke, Raziye Keskin Kurt, Ali Baloğlu
DOI: 10.17772/gp/2425
·
Ginekol Pol 2015;86(5).

open access

Vol 86, No 5 (2015)
ARTICLES

Abstract

Objective: While the relationship between platelet crit (PCT), platelet distribution width (PDW) and hypertension has been well-documented, data on the association between PCT, PDW and preeclampsia are scant at best. In our study, we aimed to investigate the possible correlation of PCT and PDW with preeclampsia and disease severity. Material and methods: A total of 110 preeclamptic and 100 healthy pregnant women were included in the study. Baseline PCT and PDW were measured using an automatic blood counterin the entire study population. Results: While there were no significant differences between the preeclampsia group and the control group in terms of hemoglobin and platelet counts, the PDW, mean platelet volume (MPV), systolic and diastolic blood pressure, proteinuria, WBC and Hs-CRP levels were significantly higher in the preeclampsia group. In addition, PCT level was significantly lower in the preeclampsia group as compared to controls. Moreover, subgroup analysis revealed that PDW and MPV levels were significantly increased in severely preeclamptic patients when compared to mildly preeclamptic patients. Conclusions: Our study results revealed that PCT and PDW levels were associated with both, the presence and severity of preeclampsia.

Abstract

Objective: While the relationship between platelet crit (PCT), platelet distribution width (PDW) and hypertension has been well-documented, data on the association between PCT, PDW and preeclampsia are scant at best. In our study, we aimed to investigate the possible correlation of PCT and PDW with preeclampsia and disease severity. Material and methods: A total of 110 preeclamptic and 100 healthy pregnant women were included in the study. Baseline PCT and PDW were measured using an automatic blood counterin the entire study population. Results: While there were no significant differences between the preeclampsia group and the control group in terms of hemoglobin and platelet counts, the PDW, mean platelet volume (MPV), systolic and diastolic blood pressure, proteinuria, WBC and Hs-CRP levels were significantly higher in the preeclampsia group. In addition, PCT level was significantly lower in the preeclampsia group as compared to controls. Moreover, subgroup analysis revealed that PDW and MPV levels were significantly increased in severely preeclamptic patients when compared to mildly preeclamptic patients. Conclusions: Our study results revealed that PCT and PDW levels were associated with both, the presence and severity of preeclampsia.
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Keywords

platelet crit / platelet distribution width / preeclampsia /

About this article
Title

Relation of platelet distribution width (PDW) and platelet crit (PCT) to preeclampsia

Journal

Ginekologia Polska

Issue

Vol 86, No 5 (2015)

Page views

1635

Article views/downloads

1642

DOI

10.17772/gp/2425

Bibliographic record

Ginekol Pol 2015;86(5).

Keywords

platelet crit / platelet distribution width / preeclampsia /

Authors

Atilla Karateke
Raziye Keskin Kurt
Ali Baloğlu

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