open access

Vol 86, No 6 (2015)
ARTICLES
Get Citation

The influence of certain plant substances and their chemopreventive activity in ovarian cancer

Radosław Kujawski, Karolina Dziekan, Hubert Wolski, Magdalena Barlik, Agnieszka Seremak-Mrozikiewicz
DOI: 10.17772/gp/2406
·
Ginekol Pol 2015;86(6).

open access

Vol 86, No 6 (2015)
ARTICLES

Abstract

A steadily growing number of studies have confirmed the beneficial effects of plant-derived substances (preparations) on the effectiveness of pharmacotherapy for ovarian cancer. A prior or parallel application of plant-derived substances and chemotherapy could be the way to strengthen the classic pharmacological treatment. Our paper presents several plant-derived substances with proven antiproliferative activities, in which phenolic and flavonoid bioactive compounds dominate, with particular emphasis on ovarian cancer cells. We are of the opinion that our paper will contribute to better understanding of the molecular basis for the positive interaction effect of concomitant application of the abovementioned plant substances with certain cytostatics. Also, this work may increase the number of preclinical in vivo experiments using these and other phenolic, flavonoid-rich plant substances to better understand their efficacy and safety and, in the future, to initiate clinical trials in this field.

Abstract

A steadily growing number of studies have confirmed the beneficial effects of plant-derived substances (preparations) on the effectiveness of pharmacotherapy for ovarian cancer. A prior or parallel application of plant-derived substances and chemotherapy could be the way to strengthen the classic pharmacological treatment. Our paper presents several plant-derived substances with proven antiproliferative activities, in which phenolic and flavonoid bioactive compounds dominate, with particular emphasis on ovarian cancer cells. We are of the opinion that our paper will contribute to better understanding of the molecular basis for the positive interaction effect of concomitant application of the abovementioned plant substances with certain cytostatics. Also, this work may increase the number of preclinical in vivo experiments using these and other phenolic, flavonoid-rich plant substances to better understand their efficacy and safety and, in the future, to initiate clinical trials in this field.
Get Citation

Keywords

ovarian cancer / plant extracts / antiproliferative activity /

About this article
Title

The influence of certain plant substances and their chemopreventive activity in ovarian cancer

Journal

Ginekologia Polska

Issue

Vol 86, No 6 (2015)

DOI

10.17772/gp/2406

Bibliographic record

Ginekol Pol 2015;86(6).

Keywords

ovarian cancer / plant extracts / antiproliferative activity /

Authors

Radosław Kujawski
Karolina Dziekan
Hubert Wolski
Magdalena Barlik
Agnieszka Seremak-Mrozikiewicz

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk
tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl