Vol 86, No 6 (2015)
ARTICLES
Efficacy and tolerability of intravenous morphine patient-controlled analgesia (PCA) in women undergoing cesarean delivery
Marta Andziak, Jarosław Beta, Michał Barwijuk, Tadeusz Issat, Artur J. Jakimiuk
DOI: 10.17772/gp/2403
·
Ginekol Pol 2015;86(6).
Vol 86, No 6 (2015)
ARTICLES
Abstract
Objectives: The aim of the study was to evaluate analgesic efficacy and tolerability of patient-controlled analgesia
(PCA) with intravenous morphine.
Material and methods: Our observational study included 50 women who underwent a Misgav-Ladach or
modified Misgav-Ladach cesarean section. Automated PCA infusion device (Medima S-PCA Syringe Pump,
Medima, Krakow, Poland) was used for postoperative pain control. Time of morphine administration or initiation
of intravenous patient-controlled analgesia (IV PCA) with morphine was recorded, as well as post-operative pain
at rest assessed by a visual analogue scale (VAS). All patients were followed up for 24 hours after discharge from
the operating room, taking into account patient records, worst pain score at rest, number of IV PCA attempts, and
drug consumption.
Results: Median of total morphine doses used during the postoperative period was 42.9mg (IQR 35.6–48.5), with
median infusion time of 687.0 min. (IQR 531.0–757.5). Pain severity and total drug consumption improved after the
first 3 hours following cesarean delivery (p<0.01). Mean number of PCA attempts per patient was 33 (IQR: 24–37),
with median of 11 placebo attempts (IQR: 3–27).
Conclusions: Patient-controlled analgesia with morphine is an efficient and acceptable analgesic method in
women undergoing cesarean section.
Abstract
Objectives: The aim of the study was to evaluate analgesic efficacy and tolerability of patient-controlled analgesia
(PCA) with intravenous morphine.
Material and methods: Our observational study included 50 women who underwent a Misgav-Ladach or
modified Misgav-Ladach cesarean section. Automated PCA infusion device (Medima S-PCA Syringe Pump,
Medima, Krakow, Poland) was used for postoperative pain control. Time of morphine administration or initiation
of intravenous patient-controlled analgesia (IV PCA) with morphine was recorded, as well as post-operative pain
at rest assessed by a visual analogue scale (VAS). All patients were followed up for 24 hours after discharge from
the operating room, taking into account patient records, worst pain score at rest, number of IV PCA attempts, and
drug consumption.
Results: Median of total morphine doses used during the postoperative period was 42.9mg (IQR 35.6–48.5), with
median infusion time of 687.0 min. (IQR 531.0–757.5). Pain severity and total drug consumption improved after the
first 3 hours following cesarean delivery (p<0.01). Mean number of PCA attempts per patient was 33 (IQR: 24–37),
with median of 11 placebo attempts (IQR: 3–27).
Conclusions: Patient-controlled analgesia with morphine is an efficient and acceptable analgesic method in
women undergoing cesarean section.
Keywords
patient-controlled analgesia / PCA / intravenous morphine / cesarean section /
Title
Efficacy and tolerability of intravenous morphine patient-controlled analgesia (PCA) in women undergoing cesarean delivery
Journal
Ginekologia Polska
Issue
Vol 86, No 6 (2015)
Page views
1052
Article views/downloads
1184
DOI
10.17772/gp/2403
Bibliographic record
Ginekol Pol 2015;86(6).
Keywords
patient-controlled analgesia / PCA / intravenous morphine / cesarean section /
Authors
Marta Andziak
Jarosław Beta
Michał Barwijuk
Tadeusz Issat
Artur J. Jakimiuk