open access

Vol 86, No 11 (2015)
ARTICLES
Get Citation

The role of miRNA in endometrial cancer - with special consideration of miRNA 205.

Miłosz Wilczyński, Justyna Danielska, Monika Dzieniecka, Andrzej Malinowski
DOI: 10.17772/gp/60077
·
Ginekol Pol 2015;86(11).

open access

Vol 86, No 11 (2015)
ARTICLES

Abstract

MiRNAs are small non-coding molecules of ribonucleic acids of approximately 22 bp length that serve as regulators of gene expression and protein translation due to interference with messenger RNA (mRNA). MiRNAs, that take part in the regulation of cell cycle and apoptosis, may be associated with carcinogenesis. Aberrant expression of miRNAs in endometrial cancer might contribute to the endometrial cancer initiation or progression, metastasis formation and influence cancer invasiveness. Specific miRNAs expressed in endometrial cancer tissues may serve as diagnostic markers of the disease, prognostic biomarkers or play an important part in oncological therapy. We aimed to describe the role of miRNAs in endometrial cancer, with special consideration of miRNA 205.

Abstract

MiRNAs are small non-coding molecules of ribonucleic acids of approximately 22 bp length that serve as regulators of gene expression and protein translation due to interference with messenger RNA (mRNA). MiRNAs, that take part in the regulation of cell cycle and apoptosis, may be associated with carcinogenesis. Aberrant expression of miRNAs in endometrial cancer might contribute to the endometrial cancer initiation or progression, metastasis formation and influence cancer invasiveness. Specific miRNAs expressed in endometrial cancer tissues may serve as diagnostic markers of the disease, prognostic biomarkers or play an important part in oncological therapy. We aimed to describe the role of miRNAs in endometrial cancer, with special consideration of miRNA 205.
Get Citation

Keywords

endometrial cancer, carcinognesis, miRNAs

About this article
Title

The role of miRNA in endometrial cancer - with special consideration of miRNA 205.

Journal

Ginekologia Polska

Issue

Vol 86, No 11 (2015)

DOI

10.17772/gp/60077

Bibliographic record

Ginekol Pol 2015;86(11).

Keywords

endometrial cancer
carcinognesis
miRNAs

Authors

Miłosz Wilczyński
Justyna Danielska
Monika Dzieniecka
Andrzej Malinowski

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk
tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl