Vol 7, No 2 (2021)
Review paper
Published online: 2021-07-21
Znaczenie witaminy D w układowych chorobach tkanki łącznej
DOI: 10.5603/FR.2021.0010
Forum Reumatol 2021;7(2):55-64.
Abstract
W ostatnich latach podkreśla się plejotropowe działanie witaminy D, zwłaszcza jej korzystny wpływ na układ kostny, układ immunologiczny oraz zmniejszenie ryzyka kancerogenezy. Jej powszechnie występujące niedobory wiążą się z częstszymi zakażeniami różnymi drobnoustrojami oraz zwiększoną śmiertelnością związaną z chorobami układu krążenia. Ze względu na regulację odpowiedzi immunologicznej zwraca się szczególną uwagę na rolę witaminy D w procesach autoimmunologicznych. W pracy omówiono wpływ witaminy D na układ immunologiczny oraz jej znaczenie w układowych chorobach tkanki łącznej (CTD, connective tissue diseases). Ze względu na korzystny wpływ witaminy D na redukcję zachorowalności i przebieg
chorób reumatycznych podkreślono konieczność jej suplementacji w przebiegu chorób reumatycznych.
Keywords: witamina Dukładowe choroby tkanki łącznejRZStoczeń rumieniowaty układowymiopatiezespół Sjögrenatwardzina układowa
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