Tom 4, Nr 4 (2024)
Praca poglądowa
Opublikowany online: 2024-12-31
Wyświetlenia strony
82
Wyświetlenia/pobrania artykułu
7
Rola wirusów w patogenezie nowotworów skóry u pacjentów z przewlekłą chorobą nerek i po transplantacji nerki
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DOI: 10.5603/fn.103293
Forum Nefrologiczne - Edukacja 2024;4(4):79-84.
Streszczenie
U pacjentów z przewlekłą chorobą nerek oraz po
przeszczepie nerki ryzyko rozwoju nowotworów
znacznie wzrasta z powodu osłabionej funkcji
układu odpornościowego. Jest to spowodowane
obecnością toksyn mocznicowych, stosowaniem
leków immunosupresyjnych oraz nawracającymi infekcjami.
Stwierdzono, że w obu grupach pacjentów
najczęściej występującymi nowotworami są raki
skóry niezwiązane z czerniakiem, w tym rak kolczystokomórkowy
(sSCC). Wirusy pozostają kluczowymi
czynnikami rakotwórczymi zarówno w przypadku
sSCC, jak i innych pierwotnych nowotworów skóry.
Słowa kluczowe: PChNchoroba nowotworowaKTxnowotwory skóry
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