Rola czynników genetycznych i immunologicznych w patogenezie raków skóry u pacjentów po przeszczepieniu narządów unaczynionych
Abstract
Skin cancers are the most common malignancies diagnosed in the population of patients after solid
organ transplantation. It is estimated that 10 years after transplantation up to 35% of the patients develop this type of tumor. The more risk factors for skin cancer development we recognize, the better preventive actions we will be able to undertake. Therefore, many studies are still being conducted to explain the mechanisms of etiopathogenesis of this disease. The following paper describes the pathogenesis of skin cancers that specifically focuses on genetic and immunological factors.
Keywords: skin cancersorgan transplantationhuman leukocyte antigensimmunosuppressionregulatory lymphocytes