The diagnostic difficulties in the evaluation of renal function in potential living kidney donors

Abstract

Evaluating the suitability of the potential living kidney donor is the procedure, that needs to be performed with responsibility and must take into account fate of the donor with only one kidney. It requires a thorough assessment of the candidate in many areas, however, it is based on the measurement of glomerular filtration function. Several methods are used for the purpose, nevertheless, all of them have their limitations. It is common to determine the concentration of serum creatinine and calculate estimated glomerular filtration rate (eGFR) on the basis of the relevant mathematical formulas. The coexistence of many factors, such as age, BMI, lifestyle or acceptable comorbidities, enforces the need for the individual examination of each candidate for the kidney donation.