Transcatheter closure of left atrial appendage as an alternative to oral anticoagulants in patients with end-stage renal disease with atrial fibrillation

Abstract

Atrial fibrillation is the most common arrhythmia in patients with chronic kidney disease (CKD). Effective method for prevention of thromboembolic complications in the general population of patients with atrial fibrillation is oral anticoagulation, however, in a substantial proportion of patients with end-stage CKD this therapy is not effective and is associated with numerous bleeding complications, it also contributes to the development of calcifications in the cardiovascular system. The aim of this study is to summarize the knowledge of anticoagulation in patients with atrial fibrillation and CKD and to provide an alternative method of treatment — transcatheter closure of left atrial appendage.