The requirement for water-soluble vitamins in patients with chronic kidney disease in the period of conservative treatment

Abstract

Vitamin deficiency is one of the forms of malnutrition. Chronic kidney disease (CKD) predisposes to this complication due to the specific diet, malabsorption, abnormal metabolism and loss of urine. Resource assessment of vitamins is difficult in chronic kidney disease due to the uncertain amount of losses associated with progressively worsening renal function. In addition, the determination of concentrations of individual water-soluble vitamins (except for vitamin B12, folic acid) is not possible under routine laboratory practice. Knowledge of the functions and resources of vitamins in patients with low GFR is fragmented and unstructured. The problem of water soluble vitamins deficiency and their supplementation in different stages of CKD require further extensive research. However, the available recommendations on intake and supplementation of water soluble vitamins should be taken into account in daily practice.