Mycophenolate mofetil treatment for lupus nephritis

Abstract

Mycophenolate mofetil (MMF) is an antiproliferative
agent, which has been used with positive clinical effect
for therapy in nephropathy due to systemic lupus
erythematosus for many years. Many randomized
controlled trials have documented the value of
the drug in induction and maintenance therapy for
active lupus nephritis. It is currently believed that the
efficacy of MMF was at least equivalent to cyclophosphamide.
That’s why it is considered to provide
an alternative for a standard treatment of lupus
nephritis. This review presents current experience
in using MMF in therapy of different types of lupus
nephropathy.