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Generalised pustular psoriasis complicated by acute respiratory failure
, 3, 2
Affiliations- Studenckie Koło Naukowe przy Klinice Dermatologii, Dermatologii Dziecięcej i Onkologicznej Uniwersytetu Medycznego w Łodzi
- Klinika Dermatologii, Dermatologii Dziecięcej i Onkologicznej Uniwersytetu Medycznego w Łodzi
- Klinika Chorób Zakaźnych i Hepatologii Uniwersytetu Medycznego w Łodzi
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Abstract
We present a case of a female admitted to the Department of Dermatology, due to a generalised pustular eruption. The first symptoms appeared after a respiratory tract infection 4 months before the hospitalisation and were treated with systemic cyclosporine. Two weeks before hospital admission the treatment was discontinued. On admission, the patient was in a good general condition with laboratory tests revealing increased CRP (C Reactive Protein) and significant anaemia. The patient underwent multiple blood transfusions, subsequently, the course of the disease was complicated by respiratory failure requiring intubation and transfer to the intensive care unit. Increased serum inflammatory markers and procalcitonin levels along with negative blood and skin cultures were observed during the hospital stay. Based on the clinical picture, laboratory tests and the course of the disease a diagnosis of generalised pustular psoriasis was made. The patient was treated with symptomatic treatment, intravenous immunoglobulin infusions and oral acitretin with gradual resolution of the skin lesions.
Abstract
We present a case of a female admitted to the Department of Dermatology, due to a generalised pustular eruption. The first symptoms appeared after a respiratory tract infection 4 months before the hospitalisation and were treated with systemic cyclosporine. Two weeks before hospital admission the treatment was discontinued. On admission, the patient was in a good general condition with laboratory tests revealing increased CRP (C Reactive Protein) and significant anaemia. The patient underwent multiple blood transfusions, subsequently, the course of the disease was complicated by respiratory failure requiring intubation and transfer to the intensive care unit. Increased serum inflammatory markers and procalcitonin levels along with negative blood and skin cultures were observed during the hospital stay. Based on the clinical picture, laboratory tests and the course of the disease a diagnosis of generalised pustular psoriasis was made. The patient was treated with symptomatic treatment, intravenous immunoglobulin infusions and oral acitretin with gradual resolution of the skin lesions.
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Keywords
generalised pustular psoriasis; acute respiratory failure; acute generalised exanthematous pustulosis
About this articleTitle
Generalised pustular psoriasis complicated by acute respiratory failure
Journal
Issue
Article type
Case report
Pages
8-11
Published online
2021-03-17
Page views
1292
Article views/downloads
40
DOI
Bibliographic record
Forum Dermatologicum 2021;7(1):8-11.
Keywords
generalised pustular psoriasis
acute respiratory failure
acute generalised exanthematous pustulosis
Authors
Magdalena Żak
Karolina Kijowska
Małgorzata Skibińska
Eliza Dalecka
Aleksandra Lesiak
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