Vol 6, No 3 (2020)
Review paper
Published online: 2020-09-10

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Differences in the clinical picture of molluscum contagiosum in immunocompromised patients

Julia Nowowiejska1, Anna Baran1, Iwona Flisiak1
Forum Dermatologicum 2020;6(3):73-76.

Abstract

Molluscum contagiosum is a viral skin disease, most frequently affecting children and sexually active or immunocompromised adults. In immunocompetent people skin lesions are self-limiting and non-intervention strategy is usually advised. In immunocompromised people, on the other hand, the clinical picture might be different, lesions are multiple and bigger in diameter, often of atypical presentation, they are more persistent and frequently difficulties considering treatment occur. In adults with diagnosed molluscum contagiosum it seems reasonable to perform an HIV test.

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References

  1. Baran A, Flisiak I. Mięczak zakaźny u dzieci — czy leczyć? Dermatologia dziecięca. 2015; 5: 18–24.
  2. Silverberg NB. Pediatric molluscum: an update. Cutis. 2019; 104(5): 301–305;E1;E2.
  3. Meza-Romero R, Navarrete-Dechent C, Downey C. Molluscum contagiosum: an update and review of new perspectives in etiology, diagnosis, and treatment. Clin Cosmet Investig Dermatol. 2019; 12: 373–381.
  4. Beutler BD, Cohen PR. Molluscum contagiosum of the eyelid: case report in a man receiving methotrexate and literature review of molluscum contagiosum in patients who are immunosuppressed secondary to methotrexate or HIV infection. Dermatol Online J. 2016; 22(3).
  5. Nguyen HP, Franz E, Stiegel KR, et al. Treatment of molluscum contagiosum in adult, pediatric, and immunodeficient populations. J Cutan Med Surg. 2014; 18(5): 299–306.
  6. pl. Tubercle. 1937; 18(12): 565.
  7. http://chpl.com.pl/data_files/Condyline_5mgroztworChPL.pdf, dostęp: 16.10.2017.
  8. Molluscum contagiosum. SpringerReference. .
  9. Ajithkumar VT, Sasidharanpillai S, Muhammed K, et al. Disseminated molluscum contagiosum following chemotherapy: A therapeutic challenge. Indian J Dermatol Venereol Leprol. 2017; 83(4): 516.
  10. Vora RV, Pilani AP, Kota RK. Extensive Giant Molluscum Contagiosum in a HIV Positive Patient. J Clin Diagn Res. 2015; 9(11): WD01–WD02.
  11. Molluscum Contagiosum Virus. Definitions. 2020.
  12. Gur I. The epidemiology of Molluscum contagiosum in HIV-seropositive patients: a unique entity or insignificant finding? Int J STD AIDS. 2008; 19(8): 503–506.
  13. Schwartz JJ, Myskowski PL. Molluscum contagiosum in patients with human immunodeficiency virus infection. A review of twenty-seven patients. J Am Acad Dermatol. 1992; 27(4): 583–588.
  14. Thompson CH, de Zwart-Steffe RT, Donovan B. Clinical and molecular aspects of molluscum contagiosum infection in HIV-1 positive patients. Int J STD AIDS. 1992; 3(2): 101–106.
  15. Hairy-cell leukaemia in a renal transplant recipient. Nephrology Dialysis Transplantation. 1996.
  16. Bhattacharjee R, Kumaran MS, Vinay K. Intralesional 5-fluorouracil to treat extensive molluscum contagiosum in an immunocompromised patient: A novel therapeutic modality. Dermatol Ther. 2018; 31(5): e12658.
  17. Thomas RM, Gillihan R, Longo M. Successful treatment of recalcitrant molluscum contagiosum in a stem cell transplant patient with Candida immunotherapy. Dermatol Ther. 2019; 32(5): e12999.
  18. Inui S, Asada H, Yoshikawa K. Successful treatment of molluscum contagiosum in the immunosuppressed adult with topical injection of streptococcal preparation OK-432. J Dermatol. 1996; 23(9): 628–630.
  19. Maiolo C, Marshman G. Zoster Immunoglobulin-VF: A Potential Treatment for Molluscum Contagiosum in Immunosuppressed Children. Pediatr Dermatol. 2015; 32(4): e193.
  20. Sung KUk, Lee HE, Choi WR, et al. Molluscum contagiosum as a skin manifestation of immune reconstitution inflammatory syndrome in an AIDS patient who is receiving HAART. Korean J Fam Med. 2012; 33(3): 182–185.
  21. Martin P. Interventions for molluscum contagiosum in people infected with human immunodeficiency virus: a systematic review. Int J Dermatol. 2016; 55(9): 956–966.