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Eosinophilic panniculitits (Wells syndrome) — a case report
Affiliations- Zakład i Klinika Dermatologii, Instytut Nauk Medycznych, Kolegium Nauk Medycznych, Uniwersytet Rzeszowski
- Zakład Patomorfologii Klinicznego Szpitala Wojewódzkiego Nr 1 im. Fryderyka Chopina w Rzeszowie
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Abstract
We present the case of a 33-year-old woman in whom recurrent and self-limiting erythemato-edematous lesions, located on the lower limbs and the trunk, have been observed for about 2 years. Physical examination, besides the erythemato-edematous skin lesions, revealed peripheral lymphadenopathy, swollen ankles, and livedo reticularis of the lower limbs and abdomen. In the laboratory tests performed, elevations of inflammatory parameters were noted. The histopathological examination of the skin lesions showed perivascular lymph-granulocytic infiltrates with a predominance of eosinophils; there were also the so-called flame figures present. The diagnosis of Wells’ syndrome was made on the basis of the overall clinical presentation. Systemic corticosteroids were started which allowed to achieve a full control of disease symptoms.
Abstract
We present the case of a 33-year-old woman in whom recurrent and self-limiting erythemato-edematous lesions, located on the lower limbs and the trunk, have been observed for about 2 years. Physical examination, besides the erythemato-edematous skin lesions, revealed peripheral lymphadenopathy, swollen ankles, and livedo reticularis of the lower limbs and abdomen. In the laboratory tests performed, elevations of inflammatory parameters were noted. The histopathological examination of the skin lesions showed perivascular lymph-granulocytic infiltrates with a predominance of eosinophils; there were also the so-called flame figures present. The diagnosis of Wells’ syndrome was made on the basis of the overall clinical presentation. Systemic corticosteroids were started which allowed to achieve a full control of disease symptoms.
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Keywords
Wells syndrome; eosinophilia; urticaria
About this articleTitle
Eosinophilic panniculitits (Wells syndrome) — a case report
Journal
Issue
Article type
Case report
Pages
109-112
Published online
2022-01-31
Page views
2743
Article views/downloads
33
DOI
Bibliographic record
Forum Dermatologicum 2021;7(4):109-112.
Keywords
Wells syndrome
eosinophilia
urticaria
Authors
Agnieszka Pszczółkowska
Elżbieta Ostańska
Adam Reich
References (7)- Heelan K, Ryan JF, Shear NH, et al. Wells syndrome (eosinophilic cellulitis): Proposed diagnostic criteria and a literature review of the drug-induced variant. J Dermatol Case Rep. 2013; 7(4): 113–120.
- Wells GC. Recurrent granulomatous dermatitis with eosinophilia. Trans St Johns Hosp Dermatol Soc. 1971; 57(1): 46–56.
- Caputo R, Marzano AV, Vezzoli P, et al. Wells syndrome in adults and children: a report of 19 cases. Arch Dermatol. 2006; 142(9): 1157–1161.
- Rajpara A, Liolios A, Fraga G, et al. Recurrent paraneoplastic Wells syndrome in a patient with metastatic renal cell cancer. Dermatology Online J. 2014; 20(6).
- Weins AB, Biedermann T, Weiss T, et al. Wells syndrome. J Dtsch Dermatol Ges. 2016; 14(10): 989–993.
- Sinno H, Lacroix JP, Lee J, et al. Diagnosis and management of eosinophilic cellulitis (Wells' syndrome): A case series and literature review. Can J Plast Surg. 2012; 20(2): 91–97.
- Räßler F, Lukács J, Elsner P. Treatment of eosinophilic cellulitis (Wells syndrome) - a systematic review. J Eur Acad Dermatol Venereol. 2016; 30(9): 1465–1479.
