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Comorbidities of hidradenitis suppurativa
- Studenckie Koło Naukowe przy Klinice Dermatologii, Dermatologii Dziecięcej i Onkologicznej Uniwersytetu Medycznego w Łodzi
- Klinika Dermatologii, Dermatologii Dziecięcej i Onkologicznej Uniwersytetu Medycznego w Łodzi
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Abstract
Hidradenitis suppurativa (HS, acne inversa) is a chronic, inflammatory skin disease characterized by painful, inflamed lesions with a tendency to sinus formation and scarring, most commonly in the axillae, inguinal folds and anogenital area. It usually begins after puberty, more often in women, obese people and smokers. HS leads to a significant deterioration in the quality of life, its treatment is long-lasting and often does not bring the satisfactory results. Numerous studies indicate that HS may be associated with a variety of concomitant diseases. It has been shown that patients with hidradenitis suppurativa have an increased risk of developing obesity, diabetes, metabolic syndrome as well as inflammatory diseases (inflammatory bowel disease, autoinflammatory syndromes). An association of HS with depression, anxiety, spondyloarthropathies, including SAPHO syndrome, have also been observed. There are reports of the coexistance of HS with SCC and some reports have suggested an association between HS and congenital keratinization disorders, Down syndrome and Behcet’s disease. It is important to pay attention to the symptoms of these diseases in patients with HS, to enable their early detection and implementation of appropriate treatment.
Abstract
Hidradenitis suppurativa (HS, acne inversa) is a chronic, inflammatory skin disease characterized by painful, inflamed lesions with a tendency to sinus formation and scarring, most commonly in the axillae, inguinal folds and anogenital area. It usually begins after puberty, more often in women, obese people and smokers. HS leads to a significant deterioration in the quality of life, its treatment is long-lasting and often does not bring the satisfactory results. Numerous studies indicate that HS may be associated with a variety of concomitant diseases. It has been shown that patients with hidradenitis suppurativa have an increased risk of developing obesity, diabetes, metabolic syndrome as well as inflammatory diseases (inflammatory bowel disease, autoinflammatory syndromes). An association of HS with depression, anxiety, spondyloarthropathies, including SAPHO syndrome, have also been observed. There are reports of the coexistance of HS with SCC and some reports have suggested an association between HS and congenital keratinization disorders, Down syndrome and Behcet’s disease. It is important to pay attention to the symptoms of these diseases in patients with HS, to enable their early detection and implementation of appropriate treatment.
Keywords
hidradenitis suppurativa; metabolic syndrome; inflammatory bowel disease; spondyloarthropathy, depression
Title
Comorbidities of hidradenitis suppurativa
Journal
Issue
Article type
Review paper
Pages
112-116
Published online
2019-10-24
Page views
9369
Article views/downloads
5475
DOI
Bibliographic record
Forum Dermatologicum 2019;5(4):112-116.
Keywords
hidradenitis suppurativa
metabolic syndrome
inflammatory bowel disease
spondyloarthropathy
depression
Authors
Magdalena Sadowska
Aleksandra Lesiak
Joanna Narbutt