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Vol 10, No 1 (2024)
Review paper
Published online: 2024-03-06
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Discoid lupus erythematosus and cutaneous squamous cell carcinoma

Michał Dec1, Hubert Arasiewicz1
DOI: 10.5603/fd.99390
·
Forum Dermatologicum 2024;10(1):18-23.
Affiliations
  1. Department of Dermatology and Vascular Anomalies, John Paul II Center of Pediatrics, Sosnowiec, Poland

open access

Vol 10, No 1 (2024)
REVIEW ARTICLES
Published online: 2024-03-06

Abstract

Discoid lupus erythematosus (DLE) is a chronic autoimmune skin disorder characterized by inflammatory skin lesions. Patients with DLE often exhibit photosensitivity, scarring, and a higher susceptibility to skin cancers. This systematic review aims to comprehensively evaluate the existing literature to better understand the relationship between DLE and cutaneous squamous cell carcinoma (cSCC). A systematic search of major medical databases was conducted to identify relevant studies published between 1978 and 2023. Studies were included if they explored the association between DLE and cSCC and reported epidemiological data, clinical features and outcomes. Evidence shows a correlation between DLE and squamous cell carcinoma. The study aimed to find literature about DLE and squamous cell carcinoma (SCC) and analyse potential risk factors. Healthcare providers should be aware of the increased cancer risk in DLE patients, emphasizing the importance of regular skin examinations and sun protection.

Abstract

Discoid lupus erythematosus (DLE) is a chronic autoimmune skin disorder characterized by inflammatory skin lesions. Patients with DLE often exhibit photosensitivity, scarring, and a higher susceptibility to skin cancers. This systematic review aims to comprehensively evaluate the existing literature to better understand the relationship between DLE and cutaneous squamous cell carcinoma (cSCC). A systematic search of major medical databases was conducted to identify relevant studies published between 1978 and 2023. Studies were included if they explored the association between DLE and cSCC and reported epidemiological data, clinical features and outcomes. Evidence shows a correlation between DLE and squamous cell carcinoma. The study aimed to find literature about DLE and squamous cell carcinoma (SCC) and analyse potential risk factors. Healthcare providers should be aware of the increased cancer risk in DLE patients, emphasizing the importance of regular skin examinations and sun protection.

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Keywords

discoid lupus erythematosus, squamous cell carcinoma, systematic review

About this article
Title

Discoid lupus erythematosus and cutaneous squamous cell carcinoma

Journal

Forum Dermatologicum

Issue

Vol 10, No 1 (2024)

Article type

Review paper

Pages

18-23

Published online

2024-03-06

Page views

100

Article views/downloads

70

DOI

10.5603/fd.99390

Bibliographic record

Forum Dermatologicum 2024;10(1):18-23.

Keywords

discoid lupus erythematosus
squamous cell carcinoma
systematic review

Authors

Michał Dec
Hubert Arasiewicz

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