Vol 10, No 1 (2024)
Case report
Published online: 2024-01-21

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A collision tumour of basal cell carcinoma and melanocytic nevus mimicking a melanoma — a case report and review of the literature

Magdalena Żychowska1, Kinga Kołcz12, Ewa Kaznowska3
Forum Dermatologicum 2024;10(1):29-31.

Abstract

A collision tumour is characterized by the presence of at least two different skin neoplasms in the same lesion. Collision skin tumours develop quite rarely. The case presents a 58-year-old woman in whom an asymmetric skin lesion of undetermined duration was noted during routine dermoscopy. The skin lesion consisted of two clinically distinct components. The patient remained under a 4-month follow-up. At the next visit, a change in the appearance of the previously present lesion was observed. The lesion was excised and submitted for histopathological examination, which was consistent with the diagnosis of a collision tumour composed of dysplastic nevus and basal cell carcinoma. This article discusses the characteristics and diagnostic difficulties in the diagnosis of collision tumours based on the available English literature. Furthermore, highlighted is the value of a non-invasive imaging modality which is dermoscopy in diagnosing not only melanoma and non-melanoma skin cancer but also complex lesions such as collision tumours.

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References

  1. Fikrle T, Divisova B, Pizinger K. Clinical-dermoscopic-histopathological correlations in collision skin tumours. Indian J Dermatol. 2021; 66(6): 577–582.
  2. Satter EK, Metcalf J, Lountzis N, et al. Tumors composed of malignant epithelial and melanocytic populations: a case series and review of the literature. J Cutan Pathol. 2009; 36(2): 211–219.
  3. Boyd AS, Rapini RP. Cutaneous collision tumors. An analysis of 69 cases and review of the literature. Am J Dermatopathol. 1994; 16(3): 253–257.
  4. Zaballos P, Álvarez Salafranca M, Medina C, et al. The usefulness of dermoscopy for the recognition of malignant collision tumors. Dermatology. 2022; 238(1): 132–139.
  5. El Gaitibi FA, Khallaayoune M, Hamich S, et al. Dermoscopy of collision tumor arising in nevus sebaceus of Jadassohn. JAAD Case Reports. 2021; 8: 74–76.
  6. Tognetti L, Cinotti E, Perrot JL, et al. Benign and malignant collision tumors of melanocytic skin lesions with hemangioma: dermoscopic and reflectance confocal microscopy features. Skin Res Technol. 2018; 24(2): 313–317.
  7. Blum A, Siggs G, Marghoob AA, et al. Collision skin lesions-results of a multicenter study of the International Dermoscopy Society (IDS). Dermatol Pract Concept. 2017; 7(4): 51–62.
  8. Ansai SI, Ogita A, Matsuda H, et al. Collision of basal cell carcinoma and melanocytic nevus with unique dermoscopic findings. J Dermatol. 2016; 43(5): 584–585.
  9. Salerni G, Lovatto L, Carrera C, et al. Correlation among dermoscopy, confocal reflectance microscopy, and histologic features of melanoma and basal cell carcinoma collision tumor. Dermatol Surg. 2011; 37(2): 275–279.
  10. Birnie AJ, Varma S. A dermatoscopically diagnosed collision tumour: malignant melanoma arising within a seborrhoeic keratosis. Clin Exp Dermatol. 2008; 33(4): 512–513.
  11. Zaballos P, Llambrich A, Puig S, et al. Dermoscopy is useful for the recognition of benign-malignant compound tumours. Br J Dermatol. 2005; 153(3): 653–656.
  12. Cornejo KM, Deng AC. Malignant melanoma within squamous cell carcinoma and basal cell carcinoma: is it a combined or collision tumor?--a case report and review of the literature. Am J Dermatopathol. 2013; 35(2): 226–234.
  13. Cascajo CD, Reichel M, Sánchez JL. Malignant neoplasms associated with seborrheic keratoses. An analysis of 54 cases. Am J Dermatopathol. 1996; 18(3): 278–282.
  14. Piérard GE, Fazaa B, Henry F, et al. Collision of primary malignant neoplasms on the skin: the connection between malignant melanoma and basal cell carcinoma. Dermatology. 1997; 194(4): 378–379.
  15. Moscarella E, Rabinovitz H, Oliviero MC, et al. The role of reflectance confocal microscopy as an aid in the diagnosis of collision tumors. Dermatology. 2013; 227(2): 109–117.