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The potential role of Helicobacter pylori and other gut dysbiosis factors in the development of rosacea
Affiliations- Department of Dermatology and Venerology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Poland
open access
Abstract
Rosacea is a chronic inflammatory disease that presents with erythema, telangiectasia, papules, or pustules. Its mechanism of onset stillneeds to be fully understood. There has been an increasing number of studies and reports confirming the beneficial influence of eradicationof Helicobacter pylori on the course of the disease. It has been recognized that the bacterium leads to the activation of the inflammatoryimmune response, resulting in the induction of symptoms similar to rosacea. Another thesis suggests a close connection between thegut–brain–skin axis, which relates to the influence of normal microbiota and gut health, and dermatological diseases. Correlations havebeen noted between the increased incidence of Crohn’s disease, ulcerative colitis, and irritable bowel syndrome in patients with rosacea.
Abstract
Rosacea is a chronic inflammatory disease that presents with erythema, telangiectasia, papules, or pustules. Its mechanism of onset stillneeds to be fully understood. There has been an increasing number of studies and reports confirming the beneficial influence of eradicationof Helicobacter pylori on the course of the disease. It has been recognized that the bacterium leads to the activation of the inflammatoryimmune response, resulting in the induction of symptoms similar to rosacea. Another thesis suggests a close connection between thegut–brain–skin axis, which relates to the influence of normal microbiota and gut health, and dermatological diseases. Correlations havebeen noted between the increased incidence of Crohn’s disease, ulcerative colitis, and irritable bowel syndrome in patients with rosacea.
Keywords
rosacea, Helicobacter pylori, eradication, microbiota
About this articleTitle
The potential role of Helicobacter pylori and other gut dysbiosis factors in the development of rosacea
Journal
Issue
Article type
Review paper
Pages
138-142
Published online
2023-09-27
Page views
476
Article views/downloads
296
DOI
Bibliographic record
Forum Dermatologicum 2023;9(4):138-142.
Keywords
rosacea
Helicobacter pylori
eradication
microbiota
Authors
Zuzanna Luiza Frydrych
Natalia Chwarścianek
Karolina Błaszak
Rafał Czajkowski
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