Vol 7, No 2 (2021)
Review paper
Published online: 2021-06-16
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Extramammary Paget’s disease: the utility of photodynamic therapy

Ewelina Mazur1, Robert Kijowski2, Adam Reich12
Forum Dermatologicum 2021;7(2):50-55.

Abstract

Extramammary Paget’s disease (EMPD) is a rare intraepithelial neoplasm which accounts for about 1% of malignant tumors in the anogenital region. It is often multifocal. Clinically it presents as a delineated erythematous plaque with typical white scales and erosions. Due to the non-specific clinical picture, the EMPD should always be considered as the differential diagnosis of pruritic lesions located in areas rich in apocrine glands and resistant to topical therapy. The golden standard in the EMPD treatment is the complete removal of the lesion with a safety margin. However, in patients with large tumors, when the surgical intervention would be mutilating for the patient, photodynamic therapy, especially in combination with imiquimod, is a good alternative and improves the patient’s quality of life.

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