Vol 3, No 4 (2017)
Case report
Published online: 2018-03-01

open access

Page views 752
Article views/downloads 2847
Get Citation

Connect on Social Media

Connect on Social Media

Diagnosis of dermatophytoses still problematic for general practitioners — 10 case studies and review of literature

Nicole Machnikowski12, Wioletta Barańska-Rybak3, Aleksandra Wilkowska3, Roman Nowicki3
Forum Dermatologicum 2017;3(4):157-165.

Abstract

Dermatophytoses, also referred to as Tinea or Ringworm, is a fungal infection of the skin caused by Trichophyton, Microsporum and Epidermophyton dermatophytes. It presents clinically as an erythematous, scaly, pruritic rash with a well-defined border (1,4). Recognizing this clinical picture is still problematic and this issue needs to be addressed. Many factors can contribute to diagnostic errors such as: the fungal infection resembling lesions of another etiology (e.g. psoriasis, discoid eczema) or the lesions presenting atypically due to the prior use of topical steroids preparations (e.g. Tinea incognito). It is now well known that potent corticosteroids increase the number of fungal hyphae on the cutaneous surface due to a suppressed immune response, all whilst giving the impression that the patient’s lesions are improving (13,17.18.19). It is preventable by performing simple mycological tests in any skin lesions without one clear etiology. A cohort of 10 cases of cutaneous dermatophytic infections with varying initial misdiagnoses were analyzed on their cutaneous presentations, clinical course, and treatments in order to raise awareness and give guidance for general practitioners.

Article available in PDF format

View PDF (Polish) Download PDF file

References

  1. Wolff K, Saavedra AP, Fitzpatrick TB. Fitzpatrick’s Color Atlas and Synopsis of Clinical Dermatology 7th ed. McGraw-Hill Medical, New York. ; 2013: 591–628.
  2. Hube B, Hay R, Brasch J, et al. Dermatomycoses and inflammation: The adaptive balance between growth, damage, and survival. J Mycol Med. 2015; 25(1): e44–e58.
  3. Fisher DA. Adverse effects of topical corticosteroid use. West J Med. 1995; 162(2): 123–126.
  4. Rosenthal JR. Fungal infections of the skin. In: Gorbach SL, Bartlett JG, Blacklow NR eds. Infectious Diseases, 3rd edn. Lippincott Williams and Wilkins, London. ; 2004: 1162–1180.
  5. Habif P. Clinical Dermatology-Sixth edition. Elsevier Health Sciences. ; 2015: 86–503.
  6. Elghblawi E. Extensive ‘Tinea Incognito’ Due to Topical Steroid: A Case Report. JMED Research. 2013: 1–3.
  7. Havlickova B, Czaika VA, Friedrich M. Epidemiological trends in skin mycoses worldwide. Mycoses. 2008; 51 Suppl 4: 2–15.
  8. Panackal AA, Halpern EF, Watson AJ. Cutaneous fungal infections in the United States: Analysis of the National Ambulatory Medical Care Survey (NAMCS) and National Hospital Ambulatory Medical Care Survey (NHAMCS), 1995-2004. Int J Dermatol. 2009; 48(7): 704–712.
  9. Ameen M. Epidemiology of superficial fungal infections. Clin Dermatol. 2010; 28(2): 197–201.
  10. Watanabe S. Dermatomycosis--classification, etiology, pathogenesis, and treatment. Nihon Rinsho. 2008 Dec; 66(12): 2285–9.
  11. Seebacher C, Bouchara JP, Mignon B. Updates on the epidemiology of dermatophyte infections. Mycopathologia. 2008; 166(5-6): 335–352.
  12. Jacobs JA, Kolbach DN, Vermeulen AH, et al. Tinea incognito due to Trichophytom rubrum after local steroid therapy. Clin Infect Dis. 2001; 33(12): E142–E144.
  13. Segal D, Wells MM, Rahalkar A, et al. A case of tinea incognito. Dermatol Online J. 2013; 19(5): 18175.
  14. Proudfoot L, Morris-Jones R. Kerion Celsi. New England Journal of Medicine. 2012; 366(12): 1142–1142.
  15. William D, Berger T, Elston D. Andrew’s Diseases of the Skin: Clinical Dermatology. Elsevier Health Sciences. 2016; 290.
  16. ‪Rycroft R‬, Robertson S. Wakelin‬ S. Dermatology: A Colour Handbook, Second Edition‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬. Manson Publishing Ltd, London. ; 2010: 222–223.
  17. Ive FA, Marks R. Tinea incognito. Br Med J. 1968; 3(5611): 149–152.
  18. Krajewska-Kulak E, Niczyporuk W, Lukaszuk C, et al. Difficulties in diagnosing and treating tinea in adults at the Department of Dermatology in Bialystok (Poland). Dermatol Nurs. 2003; 15(6): 527–30, 534.
  19. Gorani A, Schiera A, Oriani A. Case report. Rosacea-like Tinea incognito. Mycoses. 2002; 45(3-4): 135–137.
  20. Berk T, Scheinfeld N. Seborrheic dermatitis. 2010; 35(6): 348–352.
  21. Arenas R, Moreno-Coutiño G, Vera L, et al. Tinea incognito. Clin Dermatol. 2010; 28(2): 137–139.
  22. Crawford KM, Bostrom P, Russ B, et al. Pimecrolimus-induced tinea incognito. Skinmed. 2004; 3(6): 352–353.
  23. Meymandi S, Wiseman MC, Crawford RI. Tinea faciei mimicking cutaneous lupus erythematosus: a histopathologic case report. J Am Acad Dermatol. 2003; 48(2 Suppl): S7–S8.
  24. Feder HM. Tinea incognito misdiagnosed as erythema migrans. N Engl J Med. 2000; 343(1): 69.
  25. Rallis E, Koumantaki-Mathioudaki E. Pimecrolimus induced tinea incognito masquerading as intertriginous psoriasis. Mycoses. 2008; 51(1): 71–73.
  26. Lee JI, Jung HY, Lee YB, et al. A case of localized scleroderma mimicking tinea cruris. Cutis. 2013; 92(3): E5–E6.
  27. Guenova E, Hoetzenecker W, Schaller M, et al. Tinea incognito hidden under apparently treatment-resistant pemphigus foliaceus. Acta Derm Venereol. 2008; 88(3): 276–277.
  28. ; 1(67): 101–109.
  29. Garg J, Tilak R, Garg A, et al. Rapid detection of dermatophytes from skin and hair. BMC Res Notes. 2009; 2: 60.
  30. Rathi SK, D'Souza P. Rational and ethical use of topical corticosteroids based on safety and efficacy. Indian J Dermatol. 2012; 57(4): 251–259.
  31. Kastelan M, Massari LP, Brajac I. Tinea incognito due to Trichophyton rubrum--a case report. Coll Antropol. 2009; 33(2): 665–667.
  32. Şatana D. A case of Tinea incognito diagnosed coincidentally. Journal of Microbiology and Infectious Diseases. 2011; 01(02): 84–86.
  33. Siddaiah N, Erickson Q, Miller G, et al. Tacrolimus-induced tinea incognito. Cutis. 2004; 73(4): 237–238.
  34. Gupta AK, Cooper EA. Update in antifungal therapy of dermatophytosis. Mycopathologia. 2008; 166(5-6): 353–367.
  35. Medicines and Healthcare products Regulatory Agency. Oral ketoconazole: do not prescribe or use for fungal infections—risk of liver injury outweighs benefits. 2013.