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The role of the fixed combination of calcipotriol and betamethazone dipropionate in the topical therapy of psoriasis vulgaris based on current studies
open access
Abstract
Fixed combination of calcipotriol and betamethazon, due to the synergistic activity of two well-known anti-psoriatic substances, ensure high treatment efficacy, independently from psoriasis severity. The fixed combination is characterized by the rapid onset of action, and the significant clinical improvement is observed as early as within the first two weeks of therapy. An important advantage of fixed combination is the convenience of use, as the drug is given once daily and such simple dosing regimen improves patient’s compliance. It should also be underlined a good safety of the combined therapy: betamethazone reduces the risk of skin irritation due to calcipotriol, while calcipotriol reduces epidermal atrophy induced by betamethazone. All above mentioned good properties make the fixed combination the treatment of choice for topical treatment of psoriasis, both on the body, as well as on the scalp.
Abstract
Fixed combination of calcipotriol and betamethazon, due to the synergistic activity of two well-known anti-psoriatic substances, ensure high treatment efficacy, independently from psoriasis severity. The fixed combination is characterized by the rapid onset of action, and the significant clinical improvement is observed as early as within the first two weeks of therapy. An important advantage of fixed combination is the convenience of use, as the drug is given once daily and such simple dosing regimen improves patient’s compliance. It should also be underlined a good safety of the combined therapy: betamethazone reduces the risk of skin irritation due to calcipotriol, while calcipotriol reduces epidermal atrophy induced by betamethazone. All above mentioned good properties make the fixed combination the treatment of choice for topical treatment of psoriasis, both on the body, as well as on the scalp.
Keywords
psoriasis, therapy, safety
About this articleTitle
The role of the fixed combination of calcipotriol and betamethazone dipropionate in the topical therapy of psoriasis vulgaris based on current studies
Journal
Issue
Article type
Review paper
Pages
1-5
Published online
2016-05-09
Page views
806
Article views/downloads
7885
Bibliographic record
Forum Dermatologicum 2016;2(1):1-5.
Keywords
psoriasis
therapy
safety
Authors
Adam Reich
Jacek Szepietowski
