The specificity of histological techniques of frozen sections in Mohs Micrographic Surgery

Abstract

Mohs Micrographic Surgery (MMS) is a method of staged surgical excision of skin cancer based on a full analysis of histological margins, conducted mostly in “intraoperative” procedure. Fast preparation of histological sections, demonstrating the whole surgical margin (lateral and deep), requires special handling, starting with mode of surgical excision, through topographical marking of specimens, their division, to all steps of histological processing. Authors, employing the Mohs Microgpaphic Surgery in “fresh tissue” version (frozen sections) for many years, resent and discuss a number of solutions applied in this field. Particularly, the construction and operation of the own-patented, laboratory apparatus, allowing for simple and precise execution of large histological sections in MMS is discussed.